In this paper we present a genetic algorithm-based approach towards designing “enzymes” in a multi-agent system, where agents are defined as square smart blocks. In the real world an enzyme is an organic protein which catalyses a specific reaction. Here, we use it in the context of self-assembling blocks to characterize an assembly of blocks which is capable of producing another block assembly ...

This study presents a reduction of production disturbances of a shoemaking industry through discrete event simulation approach. The study is conducted at Peacock Shoe factory found in Addis Ababa, Ethiopia.  This factory faces line balancing problem that becomes production disturbance for its assembly lines. Detail time study is carried out for the selected shoe model using stopwatch. Assembly ...

given the importance of transcriptome analysis in various biological studies and considering thevast amount of whole transcriptome sequencing data, it seems necessary to develop analgorithm to assemble transcriptome data. in this study we propose an algorithm fortranscriptome assembly in the absence of a reference genome. first, the contiguous sequencesare generated using de bruijn graph with d...

the strategic pricing decisions of assembly products in assembly products supply chain are studied in this paper. firstly, a two-stage assembly products supply chain model is developed. by building nash game model, the nash equilibrium solution of pricing strategy of supplier and assemblers is obtained. next, a union decision model is built to analyze the optimal combination pricing strategy of...

Experts theorized that a Brushless Wound-rotor [Synchronous] Doubly-fed Electric Machine System (BWRSDF), which can symmetrically motor or generate with variable speed, provides higher efficiency, higher power density, higher torque density, and lower cost than any other electric machine system, including the permanent magnet electric machine system, but only with the discovery of a practical b...

Type III protein secretion machines have evolved to deliver bacterially encoded effector proteins into eukaryotic cells. Although electron microscopy has provided a detailed view of these machines in isolation or fixed samples, little is known about their organization in live bacteria. Here we report the visualization and characterization of the Salmonella type III secretion machine in live bac...

In this paper we are to present a practical application of Axiomatic Design (AD) methodology, as a roadmap to lean production, in redesigning a car body assembly line. Axiomatic Design theory provides a framework to simplify the whole problem. According to the AD principles, a hierarchical structure has been developed. The developed structure originated in lean manufacturing principles and exis...

Assembly lines are flow-oriented production systems that are of great importance in the industrial production of standard, high-volume products and even more recently, they have become commonplace in producing low-volume custom products. The main goal of designers of these lines is to increase the efficiency of the system and therefore, the assembly line balancing to achieve an optimal system i...

German machine tool manufacturers were hit hard by the recession of the nineties and by increasing world wide competition. In order to regain lost market shares, production systems and products have been re-engineered and new scheduling concepts have been developed. This article describes a new Leitstand for eeective and eecient due-date scheduling.

In eukaryotic cells, the biogenesis of spliceosomal small nuclear ribonucleoproteins (snRNPs) and likely other RNPs is mediated by an assemblyosome, the survival of motor neurons (SMN) complex. The SMN complex, composed of SMN and the Gemins (2-7), binds to the Sm proteins and to snRNAs and constructs the heptameric rings, the common cores of Sm proteins, on the Sm site (AU(56)G) of the snRNAs....