The study was undertaken to assess the dosage-mortality ratio and toxic effects of Piper guineense fruit extracts on the adults of Biomphalaria pfeifferi, the snail intermediate host of Schistosoma mansoni, which causes intestinal schistosomiasis. The result showed significant toxic effects with crude ethanol and hot water fruits extracts. The estimated lethal dose concentration by arithmetic m...

Alcoholic extract of whole fruit of Momordica charantia was prepared. Adult healthy albino rats were divided into four groups and received a dose of 6 mg/l00 gm. body weight of alloxan monohydrate. Animals of group I served as diabetic control group. The animals of II, III, and IV groups received 25 mg, 50 mg and 75 mg doses of the extract respectively for different durations. 75 mg dose showed...

Carica papaya Linn. is commonly called as paw-paw and it belongs to the family Caricaceae. Papaya possess excellent medicinal properties for treatment of different ailments. The different parts of the Carica papaya plant including leaves, seeds, latex and fruit exhibited to have medicinal value. The stem, leaf and fruit of papaya contain plenty of latex. The latex from unripe papaya fruit conta...

Leucaena leucocephala had been traditionally used to treat diabetes. The present study was designed to evaluate in vitro "insulin-like" activities of Leucaena leucocephala (Lam.) deWit. aqueous fruit extract on lipid and glucose metabolisms. The ability of the extract to stimulate adipogenesis, inhibit lipolysis, and activate radio-labeled glucose uptake was assessed using primary rat adipocyte...

BACKGROUND The plasma cholesterol and triacylglycerol lowering effects of Tamarindus indica extract have been previously described. We have also shown that the methanol extract of T. indica fruit pulp altered the expression of lipid-associated genes including ABCG5 and APOAI in HepG2 cells. In the present study, effects of the same extract on the release of proteins from the cells were investig...

OBJECTIVES The antiulcer activity of Benincasa hispida (Thunb.) Cogn. fruit was evaluated in rats against ethanol-induced gastric mucosal damage, pylorus ligated (PL) gastric ulcers, and cold restraint-stress (CRS)-induced gastric ulcer models. METHODS Petroleum ether and methanol extracts were administrated orally at the dose of 300 mg/kg, and omeprazole (reference standard) at the dose of 2...

The kidneys are important organs which have many functions in the body, including the production of hormones, absorbtion of minerals and the filtration of blood, producing urine. Their failure can be fatal, therefore, to focus the study of such herbs which may be useful in treating renal disease is the need of hour. In Pakistan, Cucumis melo and Berberis vulgaris has been commonly used for rena...

there is some report about the hypoglycemic effect of juglans rejia l. leaf in alloxan induced diabetic rats and hypoglycemic effect of its fruit peel administered intra peritoneally. thirty male wistar rats divided into five groups, to evaluate the hypoglycemic and pancreas β-cells regenerative effects of oral methanolic extracts of leaf and fruit peel of walnut. rats were made diabetic by int...