conclusions smokers with a higher bp and/or serum ggt may be at a higher risk of developing ckd. the associations of bp and serum ggt with ckd in smokers are not entirely mediated by increased insulin resistance or chronic inflammation caused by smoking. patients and methods renal functions and cvd risk factors were assessed in middle-aged male workers. the patients were comprised of 336 nonsmo...

To determine whether the increased prevalence of low serum cobalamin concentrations in elderly people represents true deficiency, serum concentrations of cobalamin and folate and of metabolites that are sensitive indicators of cobalamin deficiency were measured in 548 surviving members of the original Framingham Study cohort. Serum cobalamin concentrations < 258 pmol/L were found in 222 subject...

The present study aimed to identify key metabolites related to weight reduction in humans by studying the metabolic profiles of sera obtained from 34 participants who underwent dietary intervention with black soybean peptides (BSP) for 12 weeks. This research is a sequel to our previous work in which the effects of BSP on BMI and blood composition of lipid were investigated. Sera of the study w...

The in vivo metabolism of 2,2',3,4,4',5',6-heptachlorobiphenyl (CB183) was studied in rats and guinea pigs. Similarly to the in vitro metabolism, 3'-hydroxy (OH)-CB183 and 5-OH-CB183, were found as major metabolites in the serum and the feces of both species (serum < feces). Phenobarbital (PB)-pretreatment of animals increased the production of both metabolites, whereas 3-methylcholanthrene (MC...

This experiment was conducted to investigate the effects of different levels of oxidized fat (yellow grease) and copper sulfate on performance, carcass traits, blood metabolites and immune cells of broilers. This study was carried out as a 3 × 2 factorial experiment with 3 levels of oxidized fat (0, 2 and 4%) and 2 levels of copper sulfate (0 and 300 mg/kg) in 6 treatments, 3 replicates and 12 ...

It is widely accepted that metabolites of glucose rather than glucose itself trigger insulin release from p-cells. If so, level changes of such metabolites ought to occur in P-cells within seconds of a glucose pulse. To examine this hypothesis, glucose, glucose-6-P, fructose-diP plus triose-P, 6-P-gluconate, ATP, and P-creatine were measured in individual rat islets after intravenous infusion f...