Diseases which affect the visual pathway or the nerves to the eye muscles are often serious. This article summarises the anatomy and function of the 2nd, 3rd, 4th and 6th cranial nerves and the signs and symptoms which are important in making a correct diagnosis. N euro-ophthalmology includes the specialties of neurology and ophthalmology. Skills of both specialties are needed to assess patient...

was first, though imperfectly, described by Dumenil in 1864. But the subject dropped out of notice until 1876, when Eichhorst reported a case under the name of " Acute Progressive Neuritis," in which he found peripheral nerve degeneration without change in the brain or spinal cord. Three years afterwards, Eisenlohr and Joffroy brought forward fresh cases of the disease, followed in 1880 by cont...

hematological investigations were all within normal limits. Magnetic resonance (MR) imaging and MR angiography of the brain and orbit demonstrated compression of the right abducens nerve superiorly and laterally by dolichoectatic left VA. No other abnormal signals were seen in brainstem [Figure 1]. Owing to the fact that the right abducens nerve palsy was mild and the patient showed no diplopia...

Certain organophosphorus esters such as diisopropylfluorophosphate (DFP) cause delayed neuropathy by inhibition of neuropathy target esterase (NTE) keeping neuron in normal function. In this study, effects of neurobion alone and in combination with dexamethasone on DFP–induced delayed neuropathy were evaluated. Thirty-five mice were divided to five groups that each group consists 7 mice. Except...

Ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), showed very promisingneuroprotection action, but it suffers from high first pass metabolism and limited abilityto cross blood brain barrier. Severe gastric toxicity following oral administration furtherlimits its utility. Hence, the aim of this study was to investigate whether ibuprofen loadedmucoadhesive microemulsion (MMEI) could enha...

Background :Brain metastasesfromprimarycervical cancer are very rare.Wepresentthis report, to describe a case of brainmetastasesfromprimaryuterine cervical and conduct literaturereview about clinicalpresentation, treatment, prognosis thisdesease. Case Presentation :A 51-year-old woman, followed since 2017 for squamous cell carcinoma the cervix which she had underwent surgical treatment received...

Distal to a peripheral nerve transection, myelin degradation and Schwann cell (SC) proliferation are accompanied by a marked upregulation of brain-derived neurotrophic factor (BDNF) and a decrease of ciliary neurotrophic factor (CNTF) in non-neuronal cells. To investigate the role of SC differentiation in trophic factor regulation, we studied BDNF and CNTF expression in sciatic nerves from Trem...