نتایج جستجو برای: breast cancer cells
تعداد نتایج: 2156954 فیلتر نتایج به سال:
Background: It is well known that healthy and cancer cells are different in energy consumption. These differences lead to small changes in local temperature, so infrared thermal imaging (thermography) are applications for diagnosis of several types of cancer such as breast cancer. There are some problems in our country such as a variety of cultural and religious issues to take sample thermal im...
background: breast cancer is the most common cause of cancer in women. this tumor is hormone dependent tumor and oncologists use estrogen receptor (er), progesterone receptor (pr) and her2 for treatment of this malignancy. androgens like testosterone and their receptors (ar) have a role in the pathophysiology of breast cancer but their clinical values are not clear. method: ar expression was ev...
Background and purpose: Matrix metalloproteinase are a family of proteolytic enzymes that have specific functions in digestion of cells cohesive extra cellular matrix and also, increasing metastasis behavior of acute human tumors. It has been reported that MMPs in two forms, namely proenzyme and active enzyme in biological samples. It is distinguished that among this family, (MMP-9) Matrix Me...
OCT4B1 Dysregulation Is a Key Factor in Different Sensitivity of Normal Cells and Breast Cancer to the Curcumin
The risk of human breast cancer is concerned to cumulative exposure of the breast cells to endogenous estrogens. Strategies aiming at reducing the production of estrogens may be useful for the prevention of estrogens-related breast cancer. Several natural products with plant origin have the potential value as chemo-preventive or therapeutic agents in cancer. Flavonoids, the natural polyphenol c...
Background: NK (natural killer) and NKT (natural killer T) cells, as components of innate immune system, play a crucial role in tumor progression and dissemination. Objective: To investigate the percentages of NK cells, NKT cells, iNKT (invariant natural killer T) cells, total T lymphocytes as well as activated T lymphocytes, in tumor draining lymph nodes (TDLN...
it has been reported that cxcl12 binding to cxcr4 induces several intracellular signaling pathways, and enhances survival, proliferation, and migration of malignant cells. herein we examined the effects of anti-estrogen tamoxifen and anti-allergic tranilast drugs as a single or in combination on invasion by two in vitro invasion assays, wound-healing and matrigel invasion on mcf-7 and mda-mb-23...
background : breast cancer is one of the most frequent malignancies among iranian women. triple-negative breast cancer (tnbc) is referred to a type of breast cancer which three biomarkers of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 (her2), are negative. materials and methods: in this case control study, immunohistopathologic data of patients with tn...
background: inflammatory breast cancer (ibc), a subgroup of locally advanced breast cancer (labc), is diagnosed based on clinical findings, and seems to be different from other types of labc. the purpose of this study was to compare clinicopathological characteristics and outcomes between inflammatory and non-inflammatory labc patients at breast cancer research center (bcrc), tehran, iran. meth...
Satureja khuzestanica Jamzad (Marzeh Khuzestani in Persian) is an endemic plant that iswidely distributed in the southern part of Iran. Despite the number of papers published on thisplant, no one has focused on its anticancer effects. Therefore, the present study was designedto investigate the selective cytotoxic and anti-proliferative properties of satureja khuzestanicatotal extract (SKE). MCF...
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