The aim of this work was to investigate the effect of silica coating on bioactivity and biodegradability of hydroxyapatite. In this purpose, we firstly attempted to synthesis hydroxyapatite (HA) nanoparticles and its silica coated (Si-HA) sample in collagen matrix using calcium chloride, sodium phosphate and sodium silicate. Characterization of the sample was carried out using Fourier transform...

OBJECTIVE The objective of this study is to develop a method for selective detection of the calcific (hydroxyapatite) component in human aortic smooth muscle cells in vitro and in calcified cardiovascular tissues ex vivo. This method uses a novel optical molecular imaging contrast dye, Cy-HABP-19, to target calcified cells and tissues. METHODS A peptide that mimics the binding affinity of ost...

Data are summarized on the synthesis of hydroxyapatite (HA) by wet-chemical processes, solidstate reactions, and hydrothermal treatment. The conditions for HA preparation via precipitation from solutions of calcium chloride, dibasic ammonium phosphate, and aqueous ammonia are discussed at length. Detailed analysis of the fabrication and properties of calcium-phosphate-based ceramics is presente...

BACKGROUND Thiosulfate has been shown to inhibit vascular calcification in uremic rats and may inhibit calcification in humans with end-stage renal disease but whether this is due to a systemic or local action is unknown. The underlying mechanism is also unclear but complexation of calcium ions has been proposed. METHODS In vitro assays were used to determine the effect of thiosulfate on vasc...

the aim of this work was to investigate the effect of silica coating on bioactivity and biodegradability of hydroxyapatite. in this purpose, we firstly attempted to synthesis hydroxyapatite (ha) nanoparticles and its silica coated (si-ha) sample in collagen matrix using calcium chloride, sodium phosphate and sodium silicate. characterization of the sample was carried out using fourier transform...

This paper describes a method for preparing chitosan fibers modified with hydroxyapatite (HAp), tricalcium phosphate (β-TCP), and HAp/β-TCP nanoparticles. Fiber-grade chitosan derived from the northern shrimp (Pandalus borealis) and nanoparticles of tricalcium phosphate (β-TCP) and hydroxyapatite (HAp) suspended in a diluted chitosan solution were used in the investigation. Diluted chitosan sol...

In this study, hydroxyapatite (HA) nanocrystals have been synthesized via chemical precipitation technique. Diammonium hydrogen phosphate and calcium nitrate 4-hydrate were used as starting materials and sodium hydroxide solution was used as the agent for pH adjustment. The powder sample was evaluated by techniques such as scanning electron microscope, transmission electron microscope, Fourier ...

In the last five decades, there have been vast advances in the field of biomaterials, including ceramics, glasses, glass-ceramics and metal alloys. Dense and porous ceramics have been widely used for various biomedical applications. Current applications of bioceramics include bone grafts, spinal fusion, bone repairs, bone fillers, maxillofacial reconstruction, etc. Amongst the various calcium p...