The aim of this study was to examine the effect of crude bile on the human HepG2 and CCRF-CEM cell lines. Cells were exposed to different dilutions of bile. Antiproliferative effects were determined by the cytotoxic MTT assay. Cells undergoing apoptosis were identified by terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay. Bile administration resulted in dose-dependent c...

background: colorectal cancer (crc) is the third common malignancy all over the world. modern life styles affecting nutritional habits have been providing a potential impact on crc. this study aims to assess the nutritional characteristics in crc patients of golestan province, northeast of iran. methods: all incident crc cases (n=47) in northeast of iran (2004-2005) and a matched number of heal...

Objective(s): Breast cancer imposes a highest rate of malignancy among the women all around the world. Chitin and its derivatives such as D-glucosamine-carboxymethyl chitin and Di-hydroxy propyl chitin have immune-modulating effects and influence on innate and acquisitive immunity which lead to cell activity enhancement. The aim of this study was investigating the effect ...

Curcumin is the natural bio-active component of turmeric (Curcuma longa L.) with known therapeutic properties; nevertheless, its biological applications are limited due to its poor bioavailability. To overcome this limitation, curcumin was conjugated with silica nanoparticles. Curcumin was separated from turmeric by microwave-assisted extraction and silica nanoparticles were developed from rice...

Background & Aim: Medicinal plants can be a good replacement for common cancer treatment including chemotherapy, radiation therapy and surgery because they don’t have many side effects. The aim of this study was to investigate the effect of temperature on the free radical scavenging in the presence of medicinal plants. Experimental: For determination of free radical scavenging activity was use...