CHAT has its limits. It is a three-hour exercise. However, the real world problems of healthcare rationing and priority-setting are too complex for a three-hour exercise. What is needed, as a supplement, are sustained processes of rational democratic deliberation that can address the challenges to healthcare justice posed by costly emerging medical technologies, such as these targeted cancer th...

Introduction: Autism Spectrum Disorders (ASDs) are neuro-developmental disorders characterised by persistentimpairment in reciprocal social communication and repetitive patterns of behaviour.Objectives: To screen for ASDs children aged 16 to 30 months using M-CHAT-F (Modified Checklist Autismin Toddlers- Follow up) estimate the prevalence evaluate factors associated with ASDs.Method: Children we...

The study of the process of meaning making is central to Computer Support Collaborative Learning (CSCL). Jurong Junior College and the National Institute of Education (Singapore) Learning Sciences Laboratory have recently conducted several collaborative maths problem solving sessions using the Virtual Math Team Chat, a quasi-synchronous chat medium used to facilitate the process of mathematical...

The effect of β-amyloid aggregates on activity of choline acetyltransferase (ChAT) which is responsible for synthesizing acetylcholine (ACh) in human brain is investigated through the two-enzyme/two-compartment (2E2C) model where the presynaptic neuron is considered as compartment 1 while both the synaptic cleft and the postsynaptic neuron are considered as compartment 2 through suggesting thre...

We explored the immunoreactivity of choline acetyltransferase (ChAT) in the cranial nerve motor nuclei of the porcine rhombencephalon to reveal the cholinergic nature of these regions. In our experiments we used an immunohistochemical method for the visualization of all acetylcholine-containing structures. All studied motor nuclei contained ChAT-positive cell bodies and fibres, but the intensit...

This study investigates factors influencing live customer support chat services in Kuwait. Live Customer Support Chat represents a newly implemented type of customer service in E-commerce websites. Live Support Chat allows online agents through company’s websites to answer customer questions, complaints, and concerns on the spot through a live chat session, which bypasses the traditional e-mail...

An evaluation of a taught module within a Post-Graduate Master of Education course is reported. Participants on the course were mainly teachers learning for continuing professional development. The evaluation studies the use of ICT to provide flexible learning support. A Virtual Classroom environment was developed using WebCT and within this environment CHAT seminars were used to discuss issues...

BACKGROUND Loss of cortical choline acetyltransferase (ChAT) activity contributes to end-stage Alzheimer disease (AD) dementia. In general, ChAT activity levels are stable in the neocortex in mild to moderate AD (mAD) and there is a selective up-regulation in the superior frontal cortex (SFC) in mild cognitive impairment (MCI), indicating a transient, region-specific cholinergic neuroplastic re...

The Positive Predictive Value (PPV) of the Modified Checklist for Autism in Toddlers (M-CHAT), a parent report autism screening tool, is higher for males than for females (Ludwig et al., IMFAR 2011). Given the long waitlists and high costs for ASD evaluations, there is a need to reduce the number of false positive females on the M-CHAT. The current study examined the sex specific clinical profi...

Synchronous text-based interaction, where participants are logged in to the same virtual space at the same time, can be a useful tool for enhancing traditional classes or as part of an entirely online course. Synchronous chat, as it is also called, may not have always received the same amount of attention from educators and researchers as the various forms of asynchronous online discussion tool...