Thrombotic thrombocytopenic purpura (TTP) is a rare variant of thrombotic microangiopathy. We report case TTP in Nigerian chronic kidney disease (CKD) patient who was previously on clopidogrel. The features resolved soon after clopidogrel withdrawn. Clopidogrel cardio-protective anti-platelet drug used CKD patients at risk dyspepsia. However, its potential to cause should be recognized and cons...

background :attention deficit hyperactivity disorder (adhd) is the most common childhood neurological disorder. this disorder is more prevalent in some chronic diseases. the aim of this study was to investigate adhd in children with early stages of chronic kidney disease (ckd) and to compare it with healthy children.   methods : seventy five 5-16-year-old children with early stages of ckd (stag...

conclusions: these findings suggested that plasma adpn level is inversely associated with gfr and directly correlate with hdl-cholesterol and inversely with some, but not all metabolic factors of ckd patients who were not undergone dialysis. results: plasma adpn level was significantly higher in ckd patients than control group (p = 0.04). it was directly correlated with hdl-cholesterol (r = 0.5...

Background: Chronic kidney disease is asymptomatic until its last stages and though it is increasing globally, we are faced with paucity of a population-based model to assess this disease, particularly in developing countries. Therefore, the aim of this study was to estimate the prevalence and trends of CKD according to a new estimation method.   Methods: Using multiplier method, we est...

In chronic kidney disease (CKD) and end-stage renal disease patients cardiovascular disease is the main cause of morbidity and mortality, with incidence of cardiac related mortality increasing as renal function declines. Even after controlling for traditional cardiovascular risk factors such as smoking, age, gender, dyslipidaemia, and arterial hypertension, patients with CKD have a higher incid...

Patients with chronic kidney disease (CKD) are considered to belong to the highest risk group for the development of cardiovascular events. These patients should be subject to aggressive risk-factor modification. However, management of coronary artery disease in patients with CKD can be uniquely challenging. Many of the medications used in the treatment and prevention of coronary artery disease...

OBJECTIVE Type 2 diabetes (T2D) is the primary case of chronic kidney disease (CKD). Inflammation is associated with metabolic dysregulation in patients with T2D and CKD. Tryptophan (TRP) metabolism may have relevance to the CKD outcomes and associated symptoms. We investigated the relationships of TRP metabolism with inflammatory markers in patients with T2D and CKD. METHODS Data were collec...

Kidney disease is one of the most striking examples of health disparities in American public health. Disparities in the prevalence and progression of kidney disease are generally thought to be a function of group differences in the prevalence of kidney disease risk factors such as diabetes, hypertension, and obesity. However, the presence of these comorbidities does not completely explain the e...

Chronic kidney disease—mineral and bone disorder (CKD-MBD) is a systemic that increases the risk of morbidity mortality in dialysis patients. CKD-MBD highly prevalent patients, appropriate treatment important for improving their outcomes. Inorganic phosphate, fibroblast growth factor 23, parathyroid hormone, calciprotein particles are markers critical components effectors CKD-MBD, higher circul...