In spring 1590, book-buyers in London were confronted with a long narrative poem, ‘Disposed into twelue books, Fashioning XII. Morall vertues’, published by William Ponsonby. If they bought the poem, or leafed through it on the stationer’s stall, they encountered first a dedication ‘TO THE MOST MIGHTIE AND MAGNIFICENT EMPRESSE ELIZABETH’, then, on the following pages, the title and subtitle of ...

Background and aims: After Peroral Endoscopic Myotomy (POEM), the mucosal incision is closed with endoscopically applied clips. After each clip placement, a subsequent clipping device has to be introduced through the working channel. With the Clipmaster3, three consecutive clips can be placed without reloading which could reduce closure time. We performed a prospective study evaluating efficacy...

AIM To assess the efficacy and safety of fibrin sealant for closure of mucosal penetration at the cardia during peroral endoscopic myotomy (POEM). METHODS Twenty-four patients who underwent POEM and experienced mucosal injury of the cardia during the procedure were retrospectively identified. Of the 24 patients, 21 had mucosal penetration and 3 had only slight mucosal damage without penetrati...

MOTIVATION Expression Quantitative Trait Locus (eQTL) mapping tackles the problem of identifying variation in DNA sequence that have an effect on the transcriptional regulatory network. Major computational efforts are aimed at characterizing the joint effects of several eQTLs acting in concert to govern the expression of the same genes. Yet, progress toward a comprehensive prediction of such jo...

This paper suggests a novel form of audiovisual performancelive writingthat transforms creative writing into a realtime performing art. The process of typing a poem on the fly is captured and augmented to create an audiovisual performance that establishes natural links among the components of typing gestures, the poem being written on the fly, and audiovisual artifacts. Live writing draws upon ...