Cutaneous malignant melanoma (CMM) begins in the epidermis as the clonal emergence of melanocytes having a deregulated mitotic cycle. In a manner not yet understood, some descendents of these cells loosen their adhesions in situ and migrate into the dermis, thus initiating the processes of invasion and metastasis. These cells look and act much like macrophage-melanoma hybrids created in the lab...

‘Human factor’ is one of the most relevant and crucial aspects of software development projects management. Aiming at the performance improvement for software processes in organizations, a new model has been developed to diagnose people related processes. This new model is People-CMM and represents a complementary solution to CMM. On the other hand, existing estimation models in Software Engine...

Memory management is a critical issue for many large object-oriented applications, but in C++ only explicit memory reclamation through the delete operator is generally available. We analyse diierent possibilities for memory management in C++ and present a dynamic memory management framework which can be customised to the need of speciic applications. The framework allows full integration and co...

0 7 4 0 7 4 5 9 / 0 0 / $ 1 0 . 0 0 © 2 0 0 0 I E E E into this environment of self-proclaimed cowboys presents a challenge to even the most skilled champion. We often hear software developers say that their organization and applications are different, their projects have unique challenges, and their customers are more indecisive or inflexible than most. Because of these differences, they think...

In flowering plants the gynoecium is the female reproductive structure. In Arabidopsis thaliana ovules initiate within the developing gynoecium from meristematic tissue located along the margins of the floral carpels. When fertilized the ovules will develop into seeds. SEUSS (SEU) and AINTEGUMENTA (ANT) encode transcriptional regulators that are critical for the proper formation of ovules from ...

OBJECTIVE To determine the profile of clinical and laboratory characteristics of hospitalised HIV positive patients with neurological complications at a private hospital in Nairobi, Kenya from January 2000 to June 2005. DESIGN Retrospective observational study. SETTING The Nairobi Hospital, Nairobi, Kenya. SUBJECTS One hundred and fifty hospitalised patients. RESULTS Records of 708 HIV ...

BACKGROUND Exposure to UV radiation is associated with cutaneous malignant melanoma (CMM). In mammalian cells, UV radiation induces DNA damage that can be repaired by the nucleotide excision repair system. We designed this case-control study to determine whether DNA repair capacity (DRC) is associated with the risk of CMM and to identify risk factors that may interact biologically with DRC in t...

In this paper, a new parallel Montgomery binary exponentiation algorithm was proposed. This algorithm is based on the Montgomery modular reduction technique, binary method, common-multiplicand-multiplication (CMM) algorithm, and the canonical-signed-digit recoding (CSD) technique. By using the CMM algorithm of computing the common part from two modular multiplications, the same common part in t...

The information systems (IS) development community has focused extensively on software process improvement (SPI) programs to address the persistence of low-quality software and the perception of a software crisis. It has employed formal assessment instruments such as the capability maturity model (CMM) to gauge IS process competence and provide the impetus for software process improvement initi...

We consider the volume corrected characteristics-mixed method (VCCMM) for tracer transport problems. The volume correction adjustment maintains the local volume conservation of bulk fluids and the numerical convergence of the method. We discuss some details of implementation by considering the scheme from an algebraic point of view. We show that the volume correction adjustment is important for...