Challenges with using graphs to visualize extremely large entityrelationship datasets include visibility, usability and high degree nodes. Visual aggregation techniques, tools and easily tailorable components are needed that will support answering analytical questions with data description, characterization and interaction without loss of information. We present two case studies of prototype im...

Interactions of 3,3',4,4'-tetrahydroxybiphenyl (BPT) and three isomeric 3,3",4,4"-tetrahydroxyterphenyls (OTT, MTT, PTT) with Alzheimer’s amyloid-β peptide (Aβ) were studied by molecular dynamics simulation and molecular docking. Structural parameters such as Root-mean-square derivations (RMSD), radial distribution function (RDF), helix percentage and other physical parameters were obtained. Th...

In this paper it is presented the use of preference degrees to solve decision-making problems where linguistic preference relations are used to represent decision-makers' opinions. From a linguistic preference relation are deened a linguistic non-dominance degree, a linguistic dominance degree, and a stric domoninance degree, using linguistic quantiiers and the ordered weight linguistic aggrega...

Several fuzzy connectives, including those proposed by Lotfi Zadeh, can be seen as linear extensions of the Boolean connectives from the scale ${0,1}$ into the scale $[0,1]$. We discuss these extensions, in particular, we focus on the dualities arising from the Boolean dualities. These dualities allow to transfer the results from some particular class of extended Boolean functions, e.g., from c...

Aloe vera plant (A. vulgari and A. barbadensis) has being used traditionally as a medicinal plant for centuries. Gel from the inner central zone of the leaves and latex from pericyclic cells are used for medicinal purposes. The present study was conducted to elucidate the beneficial effects of Aloe vera juice on the platelet aggregation in cerebral microvessels of mice. Male mice were injected ...

The ingested nitrates sourced from tap water, food, chemicals and pharmaceuticals areconverted to nitrites in the body surfaces by bacteria and then, the nitrite ions can lead thestructural changing in hemoglobin. In the present work, aggregation of the purified hemoglobinin adult (HbA) and in fetus or newborn (HbF) in the presence of nitrite ions were studied.Hemoglobin aggregation was perform...

Timolol is a non-selective beta-adrenergic receptor antagonist administered for treating glaucoma, heart attacks and hypertension. In the present study, we set out to determine whether or not timolol can provoke cataract formation, thus the influence of timolol on the amyloid-type aggregation of crystallin was investigated. We then provided experimental evidence of crystallin aggregation and it...

Aggregation functions largely determine the convergence and diversity performance of multi-objective algorithms in decomposition methods. Nevertheless, traditional Tchebycheff function does not consider matching relationship between weight vectors candidate solutions. To deal with this issue, a new multiobjective state transition algorithm based on modified method (MOSTA/D) is proposed. Accordi...

objective(s): this paper describes a selective and sensitive biosensor based on the dissolution and aggregation of aptamer wrapped single-walled carbon nanotubes. we report on the direct detection of aptamer–cocaine interactions, namely between a dna aptamer and cocaine molecules based on near-infrared absorption at λ807. materials and methods: first a dna aptamer recognizing cocaine was non-co...