Fibromatosis, or extra-abdominal desmoid tumor, is a benign disease which often has an aggressive clinical course that can be difficult to treat. We performed a retrospective review of 16 patients (12 females and four males) with a mean age of 34.2 years treated with methotrexate and vinblastine for newly diagnosed or recurrent extra-abdominal desmoid tumor. The mean age of our patient cohort w...

BACKGROUND Antecedent trauma has been implicated in the causation of soft tissue tumors. Several criteria have been established to define a cause-and-effect relationship. We postulate possible mechanisms in the genesis of soft tissue tumors following antecedent traumatic injury. CASE PRESENTATION We present a 27-year-old woman with a paraspinal desmoid tumor, diagnosed 3-years following a mot...

Introduction Solid masses in the testicular and paratesticular region are rare in the pediatric age group more so in infancy. Fibrous hamartoma of infancy (FHI), juvenile xanthogranuloma, capillary hemangioma, desmoid tumor, lipoma of the cord are some of the rare pathologic findings among the benign masses in the paratesticular location. We report a case of paratesticularhamartoma in a 10 mont...

Introduction: Desmoid tumors are very rare, benign fibrous neoplasms arise from the musculoaponeurotic structures throughout the body.   Case Report: The patient was a   seven-year old boy with a large mandibular mass growing over a period of six months. His CT-scan showed a large mass, 13 cm in diameter in the cheek area extending to the neck and trachea. Biopsy was compatible with desmoid fib...

BACKGROUND Desmoid-type fibromatosis (DF) is a rare entity that predominantly involves the extremities, the trunk, and the abdominal cavity. It is a non-metastasizing, sporadic mesenchymal tumor with high tendency to recurrence and often is categorized as low-grade sarcoma. CASE REPORT We present here an extremely rare case of a mesenteric desmoid tumor (DT). A 40-year-old man presented to ou...

BACKGROUND To define the efficacy of postoperative irradiation in patients with recurrent extra-abdominal desmoid tumors in whom surgical intervention has resulted in microscopically or grossly positive surgical margins. METHODS A retrospective analysis was performed on all patients referred to the department of radiation oncology at the Detroit Medical Center with a diagnosis of recurrent ex...