possibly involved in the regulation of sleep. The present study was designed to investigate the role of brain monoamines in the sleep disorder of MMC-dosed rats and attempts to elucidate the MMC-induced sleep disorder from the standpoint of changes in the concentrations of brain monoamines. MMC was administered orally to 12 Sprague-Dawley male rats 8 weeks age at a dose of 15 mg MMC/kg body wei...

Plant stanols have been recommended in combination with individualized dietary interventions to reduce plasma cholesterol concentrations. Even though yogurt is consumed in high quantities in Turkey, it is unclear whether yogurts with plant stanols will reduce high cholesterol levels in a Turkish population. We designed this study to settle this issue. We investigated the effect of plant stanols...

OBJECTIVE To test the hypothesis that dieting, or the restriction of caloric intake, is ineffective because it increases chronic psychological stress and cortisol production--two factors that are known to cause weight gain; and to examine the respective roles of the two main behaviors that comprise dieting--monitoring one's caloric intake and restricting one's caloric intake--on psychological a...

Developmental programming by maternal stress during pregnancy is found to influence behavioral development in the offspring. The main objective of this study was to investigate the effect of maternal sodium depletion in rats during pregnancy on the development of thirst mechanisms in the offspring. Pregnant rats underwent 3 episodes of saline depletion, induced by injecting sc 10 mg of Furose...

Ultra-marathon running is supposed to increase the parameters of skeletal muscle damage and impair renal function. The purpose of this study was to investigate the effect of branched-chain amino acid supplementation on skeletal muscle damage and renal function during a 100-km ultra-marathon. Twenty-eight athletes were randomly divided into two groups, one group using branched-chain amino acid s...

The Orthodox Christian diet is unique in regularly interchanging from an omnivore to a vegetarian-type diet, and no study to date has focused on the impact of this on Fe status. Thirty-five Greek Orthodox Christian strict fasters (n 17 male, n 18 female; mean age 43.6+/-13.2 years) and twenty-four controls (n 11 male, n 13 female; mean age 39.8+/-7.6 years) were studied before (pre) and near co...

BACKGROUND Reduced rank regression (RRR) combines exploratory analysis with a-priori knowledge by including risk factors in the model. Dietary patterns, derived from RRR analysis, can be interpreted by the chosen risk factor profile and give an indication of positive or adverse health effects for a specific disease. Our aim was to assess the stability of dietary patterns derived by RRR over tim...

Medicare beneficiaries enrolled in a health maintenance organization (HMO) were randomized to a preventive services benefit package for 2 years or to usual care. At 24- and 48-month follow-ups, the treatment group had completed more advance directives, participated in more exercise, and consumed less dietary fat than the control group. Unexpectedly, more deaths occurred in the treatment group. ...

An experiment was conducted to determine the minimum levels of nonphytate P (NPP) with and without phytase that can be continuously and safely used during the growing and laying periods for diminishing P excretion to the environment. The experiment consisted of a 2 x 8 factorial arrangement of the treatments with two strains (Babcock B-300 and Hy-Line W-98) and eight diets. The birds of the con...

Introduction: Anthocyanin has cardio-protective roles, and anti-inflammatory effects. Exercise can play effective roles in this area. We assessed the effects of anthocyanin supplements on blood pressure and mean arterial pressure in combination with exercise. Methods: This randomized double-blind clinical trial conducted on 54 athletes. Participants in intervention group were taken 100 mg antho...