Objective(s): The objective of this study was to design a topical microemulsion of Vit B12 and to study the correlation between internal structure and physicochemical properties of the microemulsions. Microemulsions are thermodynamically stable mixtures of water, oil, surfactants and usually cosurfactants with several advantages for topical and transdermal drug delivery. The formul...

one of the most important parameters in evaluating a watermarking algorithm is its capacity. generally, watermarking capacity is expressed by bits per pixel (bpp) unit measure. but this measure does not show what the side effects would be on image quality, watermark robustness and capacity. in this paper we propose a three dimensional measure named capacity surface which shows the effects of ca...

In current study,a hydrogel based on biocompatible polymerwas prepared. The functionalization of polyvinyl alcohol (PVA)with epichlorohydrin(ECH) to produce epichlorohydrin-g-polyvinyl alcohol (PVA/ECH) as a suitable macroinitiator for atom transfer radical polymerization (ATRP) reaction was investigated.ThenN-vinyl pyrrolidone (NVP) waspolymerized on the surface of macroinitiatorin presence of...

Magnetic field-responsive iron oxide-loaded hollow mesoporous silica nanocapsules that exhibit high drug loading capacity were synthesized using polymer nanospheres as sacrificial templates. Due to their magnetic field induced heating and remotely triggered drug release capabilities, these hybrid nanomaterials provide an excellent platform for the combination of hyperthermia and chemotherapy.

One of the most important parameters in evaluating a watermarking algorithm is its capacity. Generally, watermarking capacity is expressed by bits per pixel (bpp) unit measure. But this measure does not show what the side effects would be on image quality, watermark robustness and capacity. In this paper we propose a three dimensional measure named Capacity surface which shows the effects of ca...

forty-five patients with chronic obstructive pulmonary disease were studied to compare the acute effects of ipratropium bromide (60 µg), salbutamol (300 µg) and placebo (3 puffs) on the forced expiratory volume in 1 sec (fev 1) and forced vital capacity (pvc). ipratropium bromide produced a significantly greater improvement than salbutamol in both fev1 and fvc at 15,60 and 180 minutes after dru...

BACKGROUND Individuals with HIV infection commonly have pulmonary function abnormalities, including airflow obstruction and diffusion impairment, which may be more prevalent among recreational drug users. To date, the relationship between drug use and pulmonary function abnormalities among those with HIV remains unclear. OBJECTIVE To determine associations between recreational drug use and ai...

conclusions this method can be appropriate to estimate sensitive issues; however, lack of understanding the method or doubting the confidentiality of the responses can lead to bias in the results. that is to say, if the instructions are introduced better, the level of trusting the method will increase and accordingly more reliable responses can be obtained. more studies under controlled conditi...

Drug resistance and toxicity constitute challenging hurdles for cancer therapy. The application of nanotechnology for anticancer drug delivery is expected to address these issues and bring new hope for cancer treatment. In this context, we established an original nanomicellar drug delivery system based on an amphiphilic dendrimer (AmDM), which could generate supramolecular micelles to effective...

Development of antimicrobial resistance (AMR) threatens our ability to treat common and life threatening infections. Identifying the emergence of AMR requires strengthening of surveillance for AMR, particularly in low and middle-income countries (LMICs) where the burden of infection is highest and health systems are least able to respond. This work aimed, through a combination of desk-based inv...