Objective(s) There are some reports that the teratogenic effects of cyclophosphamide (CPA) can be prevented by application of antioxidant drugs and stimulation of the maternal immune system. Echinacea purpurea extract is antioxidative and immunomodulator drug. Mesna (Sodium 2-mercaptoethane sulfonate) is used for decreasing side effects of CPA, especially hemorrhagic cystitis. In this study, w...

One of the most important anthropogenic pollution types in countries with oil production is soil and water contamination by petroleum. Phytoremediation is an emerging green technology for cleaning up polluted soil. A greenhouse experiment was conducted to study the effect of oil-contaminated soil on Echinacea purpurea with four concentrations of crude oil - contaminated soil: control = 0, 0.5% ...

Due to the limited availability of effective pharmaceutical products and serious side effects of the available therapy for leishmaniasis, search for useful medicinal plants is necessary. Previous studies reported preventative effect of Echinacea against Leishmania infections through immunologic stimulation. Here we tested concentrated ethanolic extract of the root of Echinacea purpurea prepared...

Nowadays green synthesis of metal nanoparticles is a developing area of research. In this study, titanium dioxide nanoparticles were biosynthesized using an aqueous solution of Echinacea purpurea herba extract as a bioreductant. This is novel and interesting method for synthesis of TiO2 nanoparticles. The prepared titanium dioxide nanoparticles were characterized using ultraviolet–visible spect...

Hepatitis B, a common infectious disease of liver, is transmitted by blood and body fluids like semen and vaginal fluid that carry hepatitis B virus (HBV).  In chronic infection, medical care is required to decrease possibility of cirrhosis and liver cancer. In the present report, the hepatoprotective effect of an Echinacea purpurea preparation (Echiherb®) has been described...