background angiogenesis is an important biological process involved in the proliferation of endothelial cells, tumor growth and metastasis. vascular endothelial growth factor (vegf) is considered as a prominent regulator of angiogenesis which exerts the aforementioned effect(s) through its respective receptors (vegfr1 and vegfr2). vegf receptors are targeted as a therapeutic candidate for cance...

The interaction between monocytes and endothelial cells is considered to play a major role in the early stage of atherosclerosis, and the involved endothelial cell micromechanics may provide us with important aspects of atherogenesis. In the present study, we evaluated (i) the endothelial cell-to-cell and cell-to-substrate gaps with the electric cell-substrate impedance sensing system, which ca...

OBJECTIVE Anti-endothelial cell antibodies in serum of patients with different inflammatory diseases can be detected by a whole cell enzyme-linked immunosorbant assay, using primary cultures of human umbilical vein endothelial cells. To avoid repeated isolation, it would be of great value if an immortal endothelial cell line could be used to perform anti-endothelial cell antibody assays. METH...

introduction: pulsed dye laser (pdl) is an important treatment for superficial infantile hemangioma, but few studies report on its cellular mechanism. the aim of this study was to evaluate alterations of serum vascular endothelial growth factor (vegf) level in infantile hemangioma (ih) patients after laser treatment and effects of pdl irradiation on human umbilical vein endothelial cells (huvec...