Mutation is the ultimate source of genetic variation. The most direct and unbiased method of studying spontaneous mutations is via mutation accumulation (MA) lines. Until recently, MA experiments were limited by the cost of sequencing and thus provided us with small numbers of mutational events and therefore imprecise estimates of rates and patterns of mutation. We used whole-genome sequencing ...

Schumpeter’s canonical depiction of the entrepreneur as an agent of social and economic change implies that entrepreneurs are especially sensitive to the social environment. We use an organizing framework based on institutional economics, in combination with lessons from cross-cultural psychology, to consider the social dimensions of entrepreneurship. The level and modes of entrepreneurial acti...

A series of pentacyclic tritperpenes found in Perilla frutescens (P. frutescens), including ursolic acid (UA), oleanolic acid (OA), corosolic acid (CA), 3-epi-corosolic acid (3-epiCA), maslinic acid (MA), and 3-epi-maslinic acid (3-epiMA) were evaluated for their effects on epidermal cell signaling, proliferation, and skin inflammation in relation to their ability to inhibit skin tumor promotio...

BACKGROUND In view of the high morbidity and mortality associated with ischemic heart disease (IHD), the estimation of individual cardiovascular risk over and above the assessment of classic risk factors, such as age, hypercholesterolemia and hypertension, is an important prerequisite for focusing preventive measures and therapeutic measures. Microalbuminuria (MA) as a marker of IHD in nondiabe...

Water-soluble monomer APEG-PG-(OH)n were produced and the Structure of APEG-PG-(OH)5 were identified by 1H-NMR. APEG-PG-(OH)n were copolymerized with maleic anhydride (MA) to synthesize no phosphate and nitrogen free calcium carbonate inhibitor MA/APEG-PG-(OH)n. The structure and thermal property of MA/APEG-PG-(OH)5 were characterized and measured by 1H-NMR, GPC and TGA. The observation shows t...

A new image compression algorithm is proposed and demonstrated in the context of structured light 3D reconstruction. Structured light images contain patterns of light, which are captured by the sensor at very high resolution. The algorithm steps involve a two level Discrete Wavelet Transformation (DWT) followed by a Discrete Cosine Transformation (DCT) to generate a DC-Column and an MA-Matrix (...

The leading electroweak MSSM two-loop corrections to the ρ-parameter are calculated. They are obtained by evaluating the two-loop self-energies of the Z and the W boson at O(GFmt ) in the limit of heavy scalar quarks. A very compact expression is derived, depending on the ratio of the CPodd Higgs boson mass, MA, and the top quark mass, mt. Expressions for the limiting cases MA ≫ mt and MA ≪ mt ...

the fabrication of a non-doped red organic light-emitting device (oled) has been developed using naturally occurring curcumin as an emissive layer of oled. in this research, the electroluminescent spectrum (el) of curcumin as a donor-acceptor-donor (d-a-d) chromophore was obtained at wavelength of 612 nm. also, the maximum external quantum efficiencies (eqe) for this device was measured and fou...