Streptococcus pneumoniae is the predominant otitis media pathogen and its prevention through effective vaccination could diminish childhood illness and antibiotic use. This paper reviews 5 pneumococcal conjugate vaccine (PCV) trials that used otitis media as an endpoint: Northern California Kaiser Permanente (NCKP; vaccine, 7-valent PCV [PCV7]-CRM); Finnish Otitis Media (FinOM; vaccines, PCV7-C...

The most common middle ear diseases are otitis media with effusion (OME), acute otitis media (AOM) and chronic suppurative otitis media (CSOM)). Diagnosing middle ear disease is based mainly on inspection of the tympanic membrane (TM) and indirect measurements of the status of the middle ear. (Tables 1, 2; Figure 1) To improve diagnostic accuracy in general practice the important factors are as...

Introduction: Tuberculous otitis media (TOM) is an uncommon, insidious, and frequently misdiagnosed form of tuberculosis (TB). In particular, TOM is usually secondary to direct transmission from adjacent organs, while the primary form has been rarely reported. The main aim of treatment is to start the patient on an antitubercular regime and early surgical intervention to decompress the facial n...

Clinical practice guideline: management of sinusitis. Pediatrics. 2001;108:798-808. 3. American Academy of Pediatrics Subcommittee on Management of Acute Otitis Media. Diagnosis and management of acute otitis media. Pediatrics. 2004;113:1451-1465. 4. Rosenfeld RM, Culpepper L, Doyle KJ, et al. Clinical practice guideline: otitis media with effusion. Otolaryngol Head Neck Surg. 2004;130(5):S95-S...

This reference guide contains highlights from the Clinical Practice Guideline, Otitis Media with Effusion in Young Children. The Otitis Media Guideline Panel, a private-sector panel of health care providers, developed the Guideline after comprehensively analyzing the research literature and current scientific knowledge of the development, diagnosis, and treatment of otitis media with effusion i...

Refractory epilepsy is a rare, long-term complication in children with acute leukemia who are receiving chemotherapy. A few studies have reported cases of several patients who developed recurrent complex partial seizures after the initiation of chemotherapy. In these cases, the cause of the refractory seizures was identified as mesial temporal lobe sclerosis. Here, we report on two patients wit...