The matching criteria were gestation (using an ultrasound crown–rump length or biparietal diameter measurement), duration of storage, and centre. Screening performance of the individual markers and combinations of markers together with maternal age was assessed using standard methods. In addition pairs of first and second trimester serum samples from 600 controls were tested to secure a larger ...

introduction since abdominal pregnancies are mostly complicated, they are usually managed by laparotomy, but laparoscopy is an alternative method which some surgeons perform instead of laparotomy; especially in advanced pregnancy. case presentation we reported a 31 year old woman with last menstrual period of 18 weeks who had supra pubic pain and vaginal bleeding. after sonographic evaluations,...

BACKGROUND Down syndrome is one of the most important causes of mental retardation in the population. In the absence of prenatal screening and diagnosis, prevalence at birth in the United States would currently exceed 1:600. The purpose of prenatal screening is to identify those women at the increased risk for an affected pregnancy and to maximize the options available to these women. TESTS A...

BACKGROUND ADAM12s (a disintegrin and metalloprotease) is a placenta-derived glycoprotein that is involved in growth and differentiation and has been shown to be a potential first-trimester and second-trimester marker of trisomy 21 and other aneuploides. Maternal ADAM12s concentrations show a considerable temporal variation with gestational age and in the initial study levels were found to be s...

BACKGROUND The aim of this study was to evaluate the interrelationships between maternal serum leptin level and body mass index (BMI) at different gestational ages or during the whole pregnancy. METHODS A total of 374 blood samples were obtained from 114 pregnant women when they visited the prenatal clinic for registration, Down syndrome screening test, 50 g oral glucose challenge test, hepat...

Background: Various studies have come to contradictory results regarding the relationship between maternal hemoglobin (Hb) level and adverse pregnancy outcomes. The present study aimed to investigate the birth outcomes among pregnant women who had normal hemoglobin levels in the first trimester of their pregnancy. Patients and Methods: In this prospective study, 108 healthy pregnant women wi...