نتایج جستجو برای: fowl adenovirus serotype 11
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BACKGROUND In 2009, pandemic H1N1 influenza virus (2009 H1N1) emerged worldwide, causing morbidity and mortality that disproportionately affected young adults. Upper respiratory infection (URI), largely due to adenovirus, is an endemic cause of morbidity in military training. Whether clinical presentations differ or excess morbidity results from coinfection is unclear. METHODS The Center for ...
Replication incompetent human adenovirus serotype 5 (HAdV-C5) has been extensively used as a delivery vehicle for gene therapy proteins and infectious disease antigens. These vectors infect replicating and nonreplicating cells, have a broad tissue tropism, elicit high immune responses and are easily purified to high titers. However, the utility of HAdV-C5 vectors as potential vaccines is limite...
TYPE 1 avian adenoviruses belong to the genus Aviadenovirus within the adenovirus family. Five species of fowl adenovirus (fAdV) (designated by the letters A to E) are recognised within the Aviadenovirus genus based largely on molecular criteria, in particular restriction enzyme fragmentation patterns and sequencing data (McFerran and McConnel Adair 2003). fAdV are common infectious agents in p...
Recombinant viruses hold promise as vectors for vaccines to prevent infectious diseases with significant global health impacts. One of their major limitations is that preexisting anti-vector neutralizing antibodies can reduce T cell responses to the insert antigens; however, the impact of vector-specific cellular immunity on subsequent insert-specific T cell responses has not been assessed in h...
"Cell type-and region-dependent coxsackie adenovirus receptor expression in the central nervous system." Abstract Model systems have shown that adenoviral vector mediated transient gene expression can potentially be applied for the treatment of brain tumours, neurodegenerative diseases and brain injuries. Most studies utilized adenovirus serotype 5 (Ad5) based vectors, which as adhesion molecul...
This is an accepted version of a paper published in Journal of Virology. This paper has been peer-reviewed but does not include the final publisher proof-corrections or journal pagination. Access to the published version may require subscription. ABSTRACT 20 Adenovirus serotype 5 (Ad5) is widely used as an oncolytic agent for cancer therapy. 21 However, its infectivity is highly dependent on th...
Astroviruses have been associated with enteric and extra-intestinal disorders in many animal species, including chickens. Here, we describe the detection characterisation of chicken astrovirus (CAstV) broilers its seroprevalence broiler breeder flocks. Based on PCR protocol, viral confirmation was carried out clinical tissue samples from chickens suffering uneven growth poor performance. The ti...
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