background and aims: inclusion body hepatitis (ibh) is one of the most important reemerging diseases in many countries with intensive poultry industries. in iran, the etiological agent of ibh (fowl adenovirus) has not been yet confirmed. the aim of this study was the molecular detection and identification of fowl adenovirus involving ibh in chicken flocks in iran. materials and methods: polymer...

We report here the complete genome sequence of virulent fowl adenovirus serotype 4 strain HB1510, isolated from a diseased chicken with hydropericardium-hepatitis syndrome in Hubei, China, in 2015. The viral genome is 43,721 bp long, and sequence analysis showed an 11-amino-acid deletion in open reading frame 29 (ORF29).

Outbreaks of hepatitis-hydropericardium syndrome (HHS) caused by fowl adenovirus serotype 4 (FAdV-4) and inclusion body hepatitis (IBH) related to FAdV-8b FAdV-11 have been increased in chickens China since 2015. Clinical concurrent infections FAdV-4, FAdV-8b, are quite common, yet there no commercially available trivalent vaccines against infection these three serotypes. In our previous study,...

Background and Aims: Inclusion body hepatitis (IBH) is one of the most important reemerging diseases in many countries with intensive poultry industries. In Iran, the etiological agent of IBH (fowl adenovirus) has not been yet confirmed. The aim of this study was the molecular detection and identification of fowl adenovirus involving IBH in chicken flocks in Iran. Materials and Methods: Polymer...

The article covers the results of pathomorphological studies broiler chickens' liver (Cobb 500 cross) spontaneously damaged by Group I fowl adenovirus. Clinical signs disease in chickens appeared on 15th day life and were manifested a sharp decrease water feed consumption. was lethargic for several days, breathing hard, mostly sitting with its head down eyes closed. During breeding period, mort...

Fowl adenoviruses (FAdV), detected during routine diagnostic investigations from 38 countries (5 continents) over a decade, were partially sequenced and grouped by phylogenetic analysis. The partial polymerase gene nucleotide sequences of the 365 fowl adenovirus isolates resulted in following species distribution: 11% FAdV-A; 3% FAdV-B; 2% FAdV-C; 34% FAdV-D; 50% FAdV-E. Noticeably, only 79 str...

Background: Inclusion body hepatitis (IBH) caused by Fowl adeno virus (FAdV), is a re-emerging threat to broilers causing considerable economic loss poultry industry worldwide. Methods: The present study investigated the IBH outbreaks in commercial broiler flocks from different regions of India between 2019- and 2021 identified serotypes associated with it molecular characterization hexon gene ...

Fowl adenovirus (FAdV) has caused significant losses in chicken flocks throughout China in recent years. However, the current understanding of the genetic and pathogenic characteristics of the FAdV epidemic in southwestern China remains poorly understood. In this study, a total of 22 strains were isolated from liver samples of diseased chickens from farms in southwestern China. Phylogenetic ana...

A recent outbreak of hepatitis-hydropericardium syndrome caused by serotype 4 fowl adenovirus (FAdV-4) has resulted in significant economic losses to the poultry industry worldwide. However, little is known about the molecular pathogenesis of FAdV-4. In this study, a novel monoclonal antibody (mAb) targeting the fiber-2 protein of FAdV-4 was generated, mAb 3C2. Indirect immunofluorescence assay...