Mental fatigue is considered to be a contributing factor responsible for numerous road accidents and various medical conditions and the efficiency and performance could be impaired during fatigue. Hence, determining how to evaluate mental fatigue is very important. In the present study, ten subjects performed a long-term visual search task with electroencephalogram recorded, and self-assessment...

The polyamines levels in autopsy brain materials of 8 patients with paranoid schizophrenia with continuous progredient type of course of disease who died of pneumonia or sharp heart deficiency at the age of 44-58 have been investigated. The results of investigations of spermine, spermidine and putrescine content in 8 autopsy brain structures of patients with schizophrenia (frontal and temporal ...

Introduction: Frontal lobe atrophy is implicated in patterns of age-related cognitive decline. However, other brain areas, including the cerebellum, support the work of the frontal lobes and are also sensitive to the effects of ageing. A relationship between cerebellar brain volume and cognitive function in older adults is reported, but no study has separated variance associated with cerebellar...

BACKGROUND Lesions of the frontal lobes may impair the capacity of patients to control otherwise intact cognitive operations in the face of ambiguous sensory input or conflicting possible responses. OBJECTIVE To address the question of whether focal lesions in different regions of the frontal lobes produced specific impairments in cognitive control. METHODS We evaluated 42 patients with chr...

Introduction:Amphetamines are central nervous system (CNS) stimulant substances and amphetamine abuse is considered a growing problem in our country. Previous studies revealed destructive effects of amphetamines on metabolism, perfusion and structure of brain. The aim of current study was evaluating regional cerebral blood flow (rCBF) disturbances in methamphetamine (MA) abuser...

OBJECTIVES To investigate the disruption of neural circuits in the frontal lobes and limbic structures in late-life depressed patients compared with healthy controls, and to examine the correlation between the degree of microstructural abnormalities of white matter and clinical symptom severity in late-life depression. METHODS Thirteen patients with late-life depression and matched control su...