نتایج جستجو برای: g2 assay
تعداد نتایج: 238546 فیلتر نتایج به سال:
امروزه سلولهای بنیادی سرطانی به عنوان یکی از عوامل اصلی و منشاء متاستاز مطرح می باشند. سلولهای بنیادی سرطانی مواد متعددی از جمله آنزیمهای پروتئازی را از خود ترشح می کنند. آنزیم کلاژناز بینابینی یا کلاژناز فیبروبلاستی عضوی از خانواده بزرگ آنزیمهای پروتئازی مذکور می باشد که با تخریب غشای پایه و ماتریکس خارج سلولی نه تنها گسترش سلولهای سرطانی را تسهیل می نماید بلکه با رهایش فاکتورهای رشد و فاکتوره...
BACKGROUND The main aim of this study was to demonstrate the antitumor potential of cucurbitacin A on A-549 NSCLC (non-small cell lung cancer cells). The effects of Cucurbitacin A on apoptotic induction, cell physic, cell cycle failure and m-TOR/PI3K/Akt signalling pathway were also investigated in the present study. MATERIALS AND METHODS MTT assay and clonogenic assay were carried out to stu...
Triple-negative breast cancer (TNBC) exhibits innate resistance to the EGFR inhibition despite high level expression of EGFR. Recently, we found that the proliferation of basal-like (BL) subtype TNBC cells is synergistically inhibited by combination of EGFR and PI3K/AKT inhibitors. On the contrary, TNBC cells of mesenchymal stem-like (MSL) subtype are resistant to these combinations. To identif...
This study aims to evaluate the radiosensitization effect of nedaplatin on nasopharyngeal carcinoma (NPC) cell lines with different Epstein-Barr virus (EBV) status. Human NPC cell lines CNE-2 (EBV-negative) and C666 (EBV-positive) were treated with 0-100 μg/mL nedaplatin, and inhibitory effects on cell viability and IC50 were calculated by MTS assay. We assessed changes in radiosensitivity of c...
An epidermoid carcinoma is a form of non-melanoma skin cancer that originates from the outer layer skin’s squamous cells. Previous studies have shown andrographis extract and andrographolide inhibit growth proliferation cells while also inducing cell cycle arrest apoptosis. The objective this study was to improve anticancer efficacy andrographolide-rich by delivering it in nanoemulgel. During f...
Phlorotannins are phenolic compounds existing in large amounts Phaeophyta, with this amount differing according to the season and collection area. There many pharmacological properties of phlorotannins, such as being antioxidant, antidiabetic, anti-cancer. In work, phlorotannins from Phaeophyta Sargassum linifolium were extracted, characterized, identified, for use an antioxidant anti-diabetic ...
Abstract Tumor Treating Fields (TTFields) are a novel, non-invasive FDA-approved treatment modality for glioblastoma (GBM) that utilises alternating electric fields. Our research aims to elucidate the effect of TTFields on cell cycle advance understanding and find novel targets increasing its efficacy. We studied progression using live-cell imaging (inovitro Live™) PIP-FUCCI-transduced GBM cell...
در این پایان نامه ابر رویه حقیقی هاف خمینه گراسمن مختلط (g2(cm+2 مطالعه می شوند. نشان می دهیم ابر رویه های حقیقی هاف (g2(cm+2 با شرط عملگر ژاکوپی ساختاری جابه جایی یعنی r?i = ?ir به ازای i=1,2,3 وجود ندارند.
The concept of the D-brane probe provides the link between gauge theory and geometry. It has proven to be one of the most important ideas among recent developments in string theory, shedding new light on strong coupling gauge theory dualities, providing a physical interpretation of previously obscure algebraic-geometric constructions, and resulting in examples of the AdS/CFT correspondence with...
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