نتایج جستجو برای: in vitro in vivo correlation

تعداد نتایج: 17021753  

Background: This study intends to present the role of rescue in vitro maturation (IVM) in polycystic ovarian syndrome(PCOS) patients undergoing in vitro fertilization (IVF) treatment who have inappropriate responses to ovarianstimulation.Materials and Methods: This was a retrospective case series study of five PCOS patients undergoing IVF treatmentconsidered for cycle ca...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده علوم پزشکی 1392

ایمونوتوکسینها برای درمان سرطان در حال توسعه هستند. آنها از آنتی بادیهای متصل به توکسین مانند اگزوتوکسین پسودوموناس تشکیل میشوند. از طرف دیگر فاکتور رشد اندوتلیال عروقی (vegf) در آنژیوژنزیس تومور نقش دارد و مهار vegfr-2 آنژیوژنزیس و رشد تومور را مهار میکند. هدف از این مطالعه تولید ایمونوتوکسین anti-vegfr2/rpe38، ارزیابی فعالیت سایتوتوکسیسیتی و مکانیسم عملکرد آن در in vitro بود. برای تولید ایمون...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه گیلان - دانشکده کشاورزی 1391

ژن fry1 در گیاه آرابیدوپسیس یک ژن واکنشگر به تنش های غیر زیستی است که آنزیمی با دو کارکرد 3 (2) 5- بیس فسفات نوکلئوتیدازی و اینوزیتول پلی فسفات 1-فسفاتازی را کد می کند. فعالیت اینوزیتول پلی فسفات 1-فسفاتازی پروتئین fry1 نشان می دهد که این پروتئین به عنوان عامل کاتابولیسم اینوزیتول 1، 4، 5، تری فسفات (ip3) در مسیر پیام رسانی فسفواینوزیتید نقش دارد. نقش دیگر fry1، تجزیه ی فسفوآدنوزین 3، 5- بیس فس...

Journal: :Development 2013
Y Albert Pan Tom Freundlich Tamily A Weissman David Schoppik X Cindy Wang Steve Zimmerman Brian Ciruna Joshua R Sanes Jeff W Lichtman Alexander F Schier

Advances in imaging and cell-labeling techniques have greatly enhanced our understanding of developmental and neurobiological processes. Among vertebrates, zebrafish is uniquely suited for in vivo imaging owing to its small size and optical translucency. However, distinguishing and following cells over extended time periods remains difficult. Previous studies have demonstrated that Cre recombin...

Journal: :nanomedicine journal 0
akram valipoor department of biology, science and research branch, islamic azad university, fars, iranسازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (islamic azad university science and research branch) kazem parivar department of biology, science and research branch, islamic azad university, tehran, iranسازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (islamic azad university science and research branch) mehrdad modaresi department of physiology, islamic azad university-khorasgan branch, isfahan, iranسازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (islamic azad university science and research branch) manoochehr messripour department of physiology, islamic azad university-khorasgan branch, isfahan, iranسازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (islamic azad university science and research branch)

objective(s):  the field of nanotechnology is rapidly expanding .the development quantum dots quantum dot (qds), show great promise for treatment and diagnosis of cancer and targeted drug delivery little data on the toxicity of qds, especially for in vivo applications, are available. as a result, concerns exist over their toxicity for in vivo applications. then, cytotoxic effects of cadmium sel...

Journal: :iranian journal of radiation research 0
m. allahverdi department of medical physics, cancer institute, tehran university of medical sciences, tehran, iran m.r. taghizadeh department of radiotherapy, imam khomeini hospital, tehran university of medical sciences, tehran, iran

abstract background: in vivo measurements of applied dose during radiotherapy treatment, is important to ensure accurate dose delivery to patients. uncertainty in dose delivery should fall within ±5% of the prescribed dose as recommended by icru. assessment of dose for radiotherapy applications performed with various types of detectors. in this study, semiconductor diodes were used which have s...

Journal: :basic and clinical cancer research 0
alireza mohammadkarim department of engineering, science and research branch, islamic azad university, tehran, iran mahmoud allahverdi department of medical physics, tehran university of medical science, tehran, iran mahbod esfehani radiotherapeutic oncology department of cancer institute hasanali nedaie department of radiotherapy, tehran university of medical science, tehran, iran alireza shirazi department of medical physics, tehran university of medical science, tehran, iran

background: delivering the maximum dose to tumor while achieving the minimum dose delivery to normal tissue; is the most important goal in external radiotherapy. diode in vivo dosimetry is widely considered to be an important tool for quality improvement of patient care in external radiotherapy. uncertainty in dose delivery should fall within 5% of the prescribed dose as recommended by internat...

Journal: :iranian red crescent medical journal 0
navid dadashpour davachi department of animal science, faculty college of agriculture and natural resources, university of tehran, karaj, ir iran ahmad zare shahneh department of animal science, faculty college of agriculture and natural resources, university of tehran, karaj, ir iran; department of animal science, faculty college of agriculture and natural resources, university of tehran, karaj, ir iran. tel: +98-9123446217, fax: +98-2612246752 hamid kohram department of animal science, faculty college of agriculture and natural resources, university of tehran, karaj, ir iran; department of clinical sciences, faculty of veterinary medicine, shahid chamran university, ahvaz, ir iran mahdi zhandi department of animal science, faculty college of agriculture and natural resources, university of tehran, karaj, ir iran saeed dashti department of animal science, faculty college of agriculture and natural resources, university of tehran, karaj, ir iran helia shamsi department of animal science, faculty college of agriculture and natural resources, university of tehran, karaj, ir iran

background to current knowledge, different oocyte's recovery method and various seasons have profound impact on in vitro embryo production (ivep). objectives the aim of this study was to define an efficient recovery method for oocytes harvesting from slaughterhouse material in different seasons, and their effects on ivep yield. materials and methods ovaries from slaughtered ewes in breeding sea...

Objective(s): Controversial results have been reported regarding the anti-tumor properties of extracellular vesicles derived from mesenchymal stem cells (MSCs). The present study was conducted to evaluate whether secretome derived from Human Wharton’s jelly mesenchymal stem cells (hWJMSCs) may stimulate or inhibit breast cancer growth in vitro and in vivo.<st...

Journal: :Vision Research 2010
Clive J. Wolsley Kathryn J. Saunders Giuliana Silvestri Roger S. Anderson

The spatial variation in central retinal function determined from mfERG was compared to co-localised measurements of cone density in two normal subjects. Individual cone cells in the parafoveal region of the retina were identified from 1 degrees x1 degrees images of the photoreceptor mosaic using a modified Heidelberg retina tomograph (HRT). The variation in cone density compared well with prev...

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