conclusions our findings indicate that umbelliprenin exhibits concentration-dependent inhibitory effects on various cell types; it is potentially toxic against the ht29, ct26, mcf-7, 4t1, a172, and gl26 cell lines, potentially harmful against bmdscs, and non-toxic against pbmcs. therefore, if our results are approved in the future, umbelliprenin can be an appropriate candidate for developing tr...

background & aim: the aim of this study was to assess the antifungal effect of the watercress extract on the growth of fusarium solani, the causal agent of potato dry rot. experimental:  this research was done in a completely randomized design with three concentrations and four replicates on potato dextrose agar (pda) culture medium. results: results of this study indicated that all conce...

background and objectives: pseudomonas aeruginosa is an opportunistic pathogen that can produce biofilm. biofilm is a complex, three dimensional structure in which microorganisms are attached to a surface and embedded in a matrix made of extracellular polymers. due to high resistance to antimicrobial agents, biofilms create difficulties in various situations in healthcare. in this study, antibi...

Organophosphate (OPs) compounds are widely used in intensive agriculture to improve production, protect crops and control diseases vectors. The main mechanism of toxicity of OPs is the inhibition of the Cholinesterase enzymes. In this study the acetylcholinestrase (AChE), butyrylcholinesterase (BChE) and specific acetylcholinestrase (SAChE) activities as potential biomarkers of exposure to OPs ...

To examine the cross-talk between NK cells and DCs in hepatitis C virus (HCV) infection, we isolated monocytes from 20 chronic HCV patients healthy controls. Monocytes were used to generate immature which pulsed with peptides (core, NS3–NS4, NS5). Four different cocultures carried out: E1, both a patient; E2, control cocultured E3, patient control; E4, control. Using flow cytometry, assessed ef...

leptadenia reticulata was reported to be used for several medicinal purposes. the present study was undertaken to evaluate anti-inflammatory, analgesic and lipid peroxidation inhibition activities of l. reticulata. the anti-inflammatory assay was performed by λ-carrageenan and formalin induced paw edema test. pro inflammatory mediators (il2, il6, tnf-α) in serum of treated and control organism ...

conclusions the results suggest that fge can improve the antibiotic sensitivity of these pathogens to some antibiotics. results fresh garlic extract displayed evident inhibition properties against c. albicans and mrsa, yet weak inhibition properties against p. aeruginosa. additionally, fge showed the potential to improve the effect of antibiotics on antibiotic resistant pathogens. the synergism...