Pharmaceutical agents and irrigating solutions are widely used in both optometric and ophthalmologic practices. Contamination of these containers or solutions could possibly pose some risk of infection to a patient. We set out to investigate the possible contamination of a representative sample of these containers in small office practices. Representative bottles of two diagnostic pharmaceutica...

INTRODUCTION Factors such as complex root canal anatomy and the vapor lock phenomenon have been shown to limit the penetration of irrigating solutions into the apical third in both in vivo and in vitro studies involving small and wide canals. Hence, the aim of this study was to determine whether the use of a patency file is related to the presence of a radiopaque irrigating solution in the apic...

We studied the effects of intraocular irrigating solutions on the 30Hz flicker electroretinogram (ERG) during extracapsular cataract surgery in 45 eyes of 35 patients. The effects of two commercially available irrigating solutions. S-MA2 (Opeguard MA) and DE-057 (BSS Plus) were compared. After irrigation and aspiration (I/A) of the residual cortex with S-MA2, ERG amplitude increased to 111.2 +/...

Acute toxicity and pharmacological actions of rosolic acid were studied. Results: ( 1) LD 50 s of rosolic acid on mice were 82 ( 78-87) mg/kg s.c. and 49 (41-58) mg/kg i.p. The animals survived after the oral administration. (2) Significant irritation on the mucosa was not observed. (3) Rosolic acid produced a rise in the blood pressure and a transient depression of respiration in the rabbit. (...