Retiming is a powerful transformation that can minimize the number of memory elements in a sequential circuit under clock period constraints. Recent research has led to the development of extremely fast algorithms for retiming edge-triggered circuits. However, level-clocked circuits have the potential to operate faster and require less memory elements than edgetriggered circuits. This paper add...

Blackboards allow various knowledge sources to be triggered in an opportunistic way, but does not allow higher modules to feedback information to lower level modules. The solution presented here remedies this shortcoming, since our Sketchboard implements reactive feedback loops. Within the Sketchboard, modules are considered from two points of view: either they build a result (a sketch, possibl...

The role of patient triggered ventilation (PTV) for the newborn was assessed using a new patient triggered ventilator, the Draeger Bablylog 8000, which incorporates significant improvements in both ventilator performance and the triggering system. Thirty three infants, median gestational age 30 weeks and postnatal age 2.5 days, were entered into the study to compare blood gases obtained during ...

In digital control applications, controllers are typically implemented in a time-triggered fashion, in which control tasks are executed periodically. This design choice is motivated by the fact that it enables the use of a well-developed theory on sampled-data systems. This design choice, however, leads to over-utilization of the available communication resources, and/or a limited lifetime of b...

Autophagy and senescence have been described as central features of cell biology, but the interplay between these mechanisms remains obscure. Using a therapeutically relevant model of DNA damage-induced senescence in human glioma cells, we demonstrated that acute treatment with temozolomide induces DNA damage, a transitory activation of PRKAA/AMPK-ULK1 and MAPK14/p38 and the sustained inhibitio...

In recent times, range based modeling and simulation techniques have emerged for systems with parameter tolerances and deviations. They are used to perform a semisymbolic simulation and to analyze the examined systems for their time domain behavior. The system quantities in such simulations are represented as range based signals using the concept of Affine Arithmetic. Transforming the range bas...

The spectrotemporal receptive field (STRF) provides a versatile and integrated (spectral and temporal) functional characterization of single cells in primary auditory cortex (AI). We explore in this paper the origin and relationship between several different ways of measuring and analyzing the STRF. Specifically, we demonstrate that STRFs measured using a spectrotemporally diverse array of broa...

The general increase in air traffic and the complexity of modern airport layouts have led to think about new system opportunities to assist pilots during maneuvers on airport surface. Two applications will be considered in this paper: guidance and control. Guidance application provides indication to the pilot to navigate on the airport surface whereas control application provides steering indic...

Musicians may have very good memory for sounds, but does that ability extend to other kinds of stimuli as well? For answers, we assessed musicians’ and non-musicians’ short-term memory for rapidly-presented, quasi-random sequences whose components varied in luminance (visual stimuli), or frequency (auditory stimuli), or both (audiovisual stimuli). In all cases, subjects judged whether a sequenc...

Simplicity of Forth language allowed to build Forth based processors. But the common sequential computational approach has performance limitation. The traditional approach to enhance the performance of processor is to increase the number of functional units that work concurrently. In this paper we examine stack's properties and propose to extend stack paradigm for parallel computing. The main g...