Nanocrystalline hydroxyapatite assembled hollow fibers (NHAHF) in the membrane form were fabricated by combining the electrospinning technique and the hydrothermal method. This novel hierarchical tubular structure of hydroxyapatite exhibited excellent protein loading capacity and long-term sustained release property.

Despite the numerous advantages of using concrete with high strength capacity, the brittle behavior of high strength concrete (HSC) and higher production cost has limited its use in the construction industry. This research aims to develop a cost-effective approach for production of high strength self-compacting concrete with desirable performance in either compressive or tensile loading conditi...

the plate girders are used in important structural systems. the earlier design of plate girders was restricted to their critical bukling capacity. experimental and theoretical studies show the plate girders with vertical stiffners can carry load over than their critical buckling loads and then in modern design codes is permitted to use post- buckling capacity of them. in this case the out- of- ...

This paper describes the production, purification, and immobilization of l-asparaginase II (ASNase II) in chitosan nanoparticles (CSNPs). ASNase II is an effective antineoplastic agent, used in the acute lymphoblastic leukemia chemotherapy. Cloned ASNase II gene (ansB) in pAED4 plasmid was transformed into Escherichia coli BL21pLysS (DE3) competent cells and expressed under optimal conditions. ...

AIM The purpose was to evaluate the effects of fatiguing eccentric contractions (EC) on calcium (Ca2+) handling properties in mammalian type I muscles. We hypothesized that EC reduces both endogenous sarcoplasmic reticulum (SR) content of releasable Ca2+ (eSRCa2+) and myofibrillar Ca2+ sensitivity. METHODS Isolated rat soleus muscles performed 30 EC bouts. Single fibres were isolated from the...

In recent years, use of biodegradable polymers based nanoparticles has received highinterest in the development of vaccines delivery vehicles. The aim of study was to preparechitosan nanoparticles (CS NPs) for loading Echis carinatus (EC) venom and evaluate theirpotential as an adjuvant and antigen delivery system on a pilot scale. CS NPs were preparedusing ionic gelation method, and their char...

       Cyproterone acetate (CA) has been loaded to liposome by solvent evaporation and thin film formation technique. The effects of some formulation variables such as temperature of organic solvent evaporation, rotary evaporator speed, volume of organic solvent, volume of balloon and temperature of hydrating buffer has been evaluated. The data showed that bigger balloon with higher surface are...

The mechanisms by which high salt intake increases vascular resistance in hypertensive humans are not clear. This study examined the possibility that salt loading produces structural changes of the forearm resistance vessels in hypertensive patients. Seventeen patients with essential hypertension were given 7 days of 70 mEq and 345 mEq sodium diet. Patients were arbitrarily divided into two gro...

In this work, SO2 adsorption on 13X and 5A was explored at different concentrations, and the results were compared to molecular simulation and models. The adsorbent saturation tests were performed at four different concentrations of 250, 500, 750, and 1000 ppm, and it was observed that saturation would take more time for higher SO2 concentrations. Grand Canonical Monte Carlo method was used for...

In the past decade, many strategies have been developed to enhance oral drug delivery. Different techniques were investigated, amongst those the use of permeation enhancers such surfactants and biodegradable polymers were studied more extensively. Chitosan derivatives have been studied as permeation enhancer in free soluble form and as nanoparticulate systems. The aim of the current work wa...