We report the facile synthesis of arginine-glycine-aspartic acid (RGD) peptide-targeted iron oxide (Fe3O4) nanoparticles (NPs) with ultrahigh relaxivity for in vivo tumor magnetic resonance (MR) imaging. In this study, stable polyethyleneimine (PEI)-coated Fe3O4 NPs were first prepared by a mild reduction route. The formed aminated Fe3O4 NPs with PEI coating were sequentially conjugated with fl...

Homoharringtonine (HHT), a natural cephalotaxine alkaloid, has been used in the People's Republic of China for treatment of leukemia for >3 decades. Here, we employed magnetic Fe3O4 nanoparticles (MNP-Fe3O4) to improve the therapeutic effect of HHT and investigated its biological effects. Within a certain range of concentrations, the HHT-MNP-Fe3O4 showed a more enhanced inhibitory effect on the...

Stable magnetic nanofluids containing Fe3O4@Polypyrrole (PPy) nanoparticles (NPs) were prepared by using a facile and novel method, in which one-pot route was used. FeCl3·6H2O was applied as the iron source, and the oxidizing agent to produce PPy. Trisodium citrate (Na3cit) was used as the reducing reagent to form Fe3O4 NPs. The as-prepared nanofluid can keep long-term stability. The Fe3O4@PPy ...

OBJECTIVE This study aims to investigate the potential benefit of combination therapy with magnetic nanoparticles of Fe3O4 (Fe3O4-MNP) and gambogic acid (GA) on SMMC-7721 cells. METHODS The inhibition of proliferation of SMMC-7721 cells was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Cell apoptosis was calculated and analyzed by flow cytometry, and the exp...

in this work firstly fe3o4 nanoparticles were synthesized via a sono-chemical method. at the second step magnesium hydroxide shell was synthesized on the magnetite-core under ultrasonic waves. for preparation fe3o4-mgo the product was calcinated at 400 ºc for 2h. properties of the product were examined by x-ray diffraction pattern (xrd), scanning electron microscope (sem) and fourier transform ...

TiO2 /Fe3O4 nanocomposites with various TiO2:Fe3O4 ratios were synthesized by an ultrasonic-assisted deposition-precipitation method and their UV-light decolorization of Congo dye and magnetic separation were investigated. The nanocomposite samples were characterized by scanning electron microscopy (SEM), powder X-ray diffraction (XRD), surface area analayzer (BET) and Fourier transform infrare...

We report highly efficient magnetically recoverable photocatalysts through combination of Fe3O4/ZnO with AgI and Ag2CO3, as narrow band gap semiconductors. The resultant photocatalysts were characterized by XRD, EDX, SEM. TEM, UV–vis DRS, FT-IR, PL, and VSM instruments. Under visible-light illumination, the nanocomposite with 1:6 weight ratio of Fe3O4 to ZnO/AgI/Ag2CO3 exhibited superior activi...

A novel type of pH-responsive biodegradable copolymer was developed based on methyloxy-poly(ethylene glycol)-block-poly[dopamine-2-(dibutylamino) ethylamine-l-glutamate] (mPEG-b-P(DPA-DE)LG) and applied to act as an intelligent nanocarrier system for magnetic resonance imaging (MRI). The mPEG-b-P(DPA-DE)LG copolymer was synthesized by a typical ring opening polymerization of N-carboxyanhydrides...

an efficient and simple method for the preparation of si-imidazole-hso4 functionalized magnetic fe3o4 nanoparticles (si-im-hso4 mnps) and used as an efficient and reusable magnetic catalysts for the regioselective ring opening of epoxides under green conditions in water. this catalyst was used for the ring opening of epoxide corresponding to the thiocyanohydrins and azidohydrines. compared to t...