نتایج جستجو برای: material requirement planning mrp

تعداد نتایج: 714840  

1998
Marc Braun Sybille Möhle

At our research institute, we explored to what extent it is possible to build complex applications with standard software. Using Microsoft Office packages we established an MRP II-system which contains all important modules. For small to medium-sized enterprises (SME) it might be an alternative to today’s planning systems, most of which focusing on organizing and supervising complex manufacturi...

Journal: :Molecular pharmacology 1997
B D Stride C E Grant D W Loe D R Hipfner S P Cole R G Deeley

Overexpression of the human multidrug-resistance protein (MRP) causes a form of multidrug resistance similar to that conferred by P-glycoprotein, although the two proteins are only distantly related. In contrast to P-glycoprotein, human MRP has also been shown to be a primary active transporter of a structurally diverse range of organic anionic conjugates, some of which may be physiological sub...

2009
Mohamed Aly Ould Louly Alexandre Dolgui

This paper considers component supply planning for assembly systems where several types of components are needed to produce one finished product. The actual component lead times have random deviations. The aim of this study is to find the optimal MRP offsetting when the Periodic Order Quantity (POQ) policy is used. The proposed model and algorithms minimize the sum of the setup and average hold...

Journal: :The Journal of clinical investigation 2014
Yunmei Wang Chao Fang Huiyun Gao Matthew L Bilodeau Zijie Zhang Kevin Croce Shijian Liu Toshifumi Morooka Masashi Sakuma Kohsuke Nakajima Shuichi Yoneda Can Shi David Zidar Patrick Andre Gillian Stephens Roy L Silverstein Nancy Hogg Alvin H Schmaier Daniel I Simon

Expression of the gene encoding the S100 calcium-modulated protein family member MRP-14 (also known as S100A9) is elevated in platelets from patients presenting with acute myocardial infarction (MI) compared with those from patients with stable coronary artery disease; however, a causal role for MRP-14 in acute coronary syndromes has not been established. Here, using multiple models of vascular...

Journal: :Journal of Mathematics and Computer Science 2010

Journal: :Drug metabolism and disposition: the biological fate of chemicals 1999
H Gutmann M Török G Fricker J Huwyler C Beglinger J Drewe

Multidrug resistance-associated protein (MRP) is a transport system that is involved in the elimination of xenobiotics and biologically active endogenous substrates. Recently, the presence of MRP has been demonstrated in cultured brain capillary endothelial cells (BCECs). The time-dependent, functional expression of MRP in porcine BCECs was investigated to assess the value of this cell culture ...

This study is conducted to developed innovative production planning and control strategies to manufacturing industries so as to improve production performance and competitiveness of basic metal sectors Though the study was conducted through field observation and questioner used as primary data and literature review on research articles, books, and electronic-sources which used as secondar...

Journal: :Computers & Industrial Engineering 2023

With today's rapidly changing supply chain environment, it is essential to include uncertainty in an explicit manner planning models. Therefore, we propose a stochastic model for tactical of the Crude Oil Supply Chain (COSC) under cost and demand uncertainties. The mathematical considers multi-echelon with multi-products multi-period horizon. It integrates inventory backorder penalties. A Sampl...

Journal: :Computers & Industrial Engineering 2010
Cemalettin Öztürk Arslan M. Örnek

In this paper, we propose a mixed integer programming (MIP) model for a multi-level multi resource capacitated lot sizing and scheduling problem with a set of constraints to track dependent demand balances, that is, the amount left over after allocating the available inventory to the dependent demands. A part of this leftover amount may be kept as a reservation quantity to meet dependent demand...

Journal: :Circulation 2009
Kevin Croce Huiyun Gao Yunmei Wang Toshifumi Mooroka Masashi Sakuma Can Shi Galina K Sukhova René R S Packard Nancy Hogg Peter Libby Daniel I Simon

BACKGROUND Myeloid-related protein (MRP)-8 (S100A8) and MRP-14 (S100A9) are members of the S100 family of calcium-modulated proteins that regulate myeloid cell function and control inflammation, in part, through activation of Toll-like receptor-4 and the receptor for advanced glycation end products. A transcriptional profiling approach in patients with acute coronary syndromes identified MRP-14...

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