BACKGROUND Psychiatric comorbidity of autism spectrum disorder (ASD) has not been well examined. METHODS Mood disorders in 44 consecutive outpatients with high-functioning ASD were examined at a university hospital according to DSM-IV. Inclusion criteria were an IQ of 70 or higher on the Wechsler Intelligence Scale and age of 12 years or over. RESULTS Sixteen patients (36.4%) were diagnosed...

OBJECTIVE Self-mutilation has traditionally been associated with borderline personality disorder, and seldom examined separately from suicide attempts. Clinical experience suggests that self-mutilation is common in bipolar disorder. METHODS A family study was conducted on the molecular genetics of depression and personality, in which the proband had been treated for depression. All probands a...

a growing number of observational and epidemiological studies have suggested that mental illness, in particular mood disorders, is associated with decreased dietary intake and/or cellular abundance of omega-3 polyunsaturated fatty acids (pufa). this has prompted researchers to test the efficacy of omega-3 pufa in a range of different psychiatric disorders. we have critically reviewed the double...

There is some discussion concerning the phenomenology of pediatric bipolar disorder. This condition is marked by irritability and sudden mood swings, and has no specific diagnostic criteria. Disagreement is even greater for bipolar disorder in preschool age. We report the case of a child of four years and nine months with diagnosis of bipolar disorder not otherwise specified. Predominant sympto...

BACKGROUND Women with bipolar disorder have a high risk of relapse following childbirth. The risk of relapse can be reduced by mood stabilisers, but they are potentially harmful to the developing fetus. OBJECTIVE The objective of this article is to provide an up-to-date review of the strategies for managing women with bipolar disorder over the perinatal period. DISCUSSION Discussing the ris...

IMPORTANCE There is a paucity of research among African Americans and rural residents. Little is known about the association between urbanicity and depression or about the interaction of urbanicity, race/ethnicity, and sex on depression and mood disorder prevalence. OBJECTIVE To examine the interaction of urbanicity and race/ethnicity on lifetime and 12-month major depressive disorder (MDD) a...

BACKGROUND Anorexia Nervosa (AN) is a psychiatric illness associated with a number of personality disturbances. However, whether these personality characteristics are related to eating disorder symptomatology or emotion regulation is unclear. The aim of this study was to investigate these relationships. RESULTS Twenty-four individuals with AN and 25 age- and premorbid intelligence-matched con...

Introduction Disruptive Mood Dysregulation Disorder (DMDD) is a new disorder that has been added to the category of mood disorders in fifth Diagnostic and Statistical Manual Mental Disorders distinguish chronic non-periodic irritability from periodic bipolar disorder. The main characteristic DMDD severe irritability. Because it diagnostic entity, little research done on literature subject still...

The mood disorders major depressive disorder and bipolar disorder are prevalent, are inadequately treated, and little is known about their etiologies. A better understanding of the causes of mood disorders would benefit from improved animal models of mood disorders, which now rely on behavioral measurements. This review considers the limitations in relating measures of rodent behaviors to mood ...