نتایج جستجو برای: morphea profunda
تعداد نتایج: 2289 فیلتر نتایج به سال:
Figure 1. Photograph of the legs. A large, thickened, firm, hyper/hypopigmented plaque is evident on the left leg. Figure 2. Biopsies of affected skin (A) and contiguous tibialis anterior muscle and fascia from the left leg (B–D). (A) The der-mal collagen is thickened, packed, and hyalinized. The subcutaneous fat is extensively replaced by collagen, and perivascular inflammatory infiltrates are...
Herein we report successful treatment of an adolescent Caucasian female with severe progressive localized scleroderma (mixed subtype, including generalized morphea and linear scleroderma of the trunk/limb) using infliximab and leflunomide. The patient demonstrated improvement after the first 9 months of therapy based on her clinical examination, objective measures, and patient and parent global...
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