background :    acinetobacter baumannii has become one of the most important causes of nosocomial infections in recent years. the organism seems to be resistant to most classes of antibiotics. carbapenems are considered the most effective drugs for treatment of these infections. however, increasing emergence of carbapenem resistant a. baumannii has become a major healthcare problem.   methods :...

conclusions according to the findings of our study, there were diverse and high-level resistant p. aeruginosa strains in the major burn center in khuzestan. therefore, we faced troubles controlling the diverse p. aeruginosa clones in the burn patients. methods in a cross sectional study, a total of 75 strains of p. aeruginosa were isolated from burn patients at taleghani hospital, which is the ...

background and objectives: to investigate coagulase gene polymorphisms of mrsa and mssa isolates from shiraz teaching hospitals from 2011 to 2012. materials and methods: a total of 302 isolates of staphylococcus aureus were collected from clinical specimens in three major teaching hospitals and confirmed on the basis of morphological characteristics and biochemical tests. the isolates were subj...

streptococcus pneumoniae is an important problem worldwide and nasopharyngeal colonization plays significant role in pneumococcal infections. the aims of this study were to determine the nasopharyngeal colonization rate, serotyping, antibiotics susceptibility and study the risk factors for nasopharyngeal colonization with s. pneumoniae in students in kashan, iran.a cross-sectional study was con...

shigella sonnei is considered as a major cause of diarrheal disease in both developing and developed countries. iran is one of the endemic areas of shigellosis. the present study was undertaken to investigate the antibiotic susceptibility and genetic relatedness of s. sonnei strains isolated from pediatric patients in tehran, iran.the study included all s. sonnei strains isolated from pediatric...

results two bacterial types, st208, and st218, were identified in all 140 samples. the st208 mainly came from icu and department of respiratory medicine, while st218 from department of plastic surgery; 70.21% of st208 and 84.78% of st218 were carbapenem-resistant acinetobacter baumannii (crab) and carbapenem-susceptible acinetobacter baumannii (csab), respectively. multidrug-resistance genes in...

background and objectives: patients at intensive-care-unit (icu) are at risk of acquiring nosocomial infections which contributes to higher rates. approximately 25% of all hospital infections and 90% of outbreaks occur in icus. multi-resistant gram-negative rods are important pathogens in icus, causing high rate of mortality. the purpose of this study was to investigate the antimicrobial resist...

conclusions the present study showed that bla oxa-23-like was the most frequent carbapenemase identified among carbapenem-resistant a. baumannii isolated in tehran hospitals. evaluation of antibiotic resistance genes in a. baumannii, is necessary to control further dissemination of these antibiotic resistant genes. results results showed that 123 of 131 (93.89%) acinetobacter species, possessed...

The evolution of antibiotic resistance in microbes poses one of the greatest challenges to the management of human health. Because addressing the problem experimentally has been difficult, research on strategies to slow the evolution of resistance through the rational use of antibiotics has resorted to mathematical and computational models. However, despite many advances, several questions rema...

The sexually transmitted bacterium Neisseria gonorrhoeae has developed resistance to all antibiotic classes that have been used for treatment and strains resistant to multiple antibiotic classes have evolved. In many countries, there is only one antibiotic remaining for empirical N. gonorrhoeae treatment, and antibiotic management to counteract resistance spread is urgently needed. Understandin...