نتایج جستجو برای: muscular function

تعداد نتایج: 1248677  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه بوعلی سینا - دانشکده علوم پایه 1391

abstract: in this thesis, we focus to class of convex optimization problem whose objective function is given as a linear function and a convex function of a linear transformation of the decision variables and whose feasible region is a polytope. we show that there exists an optimal solution to this class of problems on a face of the constraint polytope of feasible region. based on this, we dev...

رحمانی نیا, فرهاد, محبی, حمید, پاشازاده, فرهاد,

Background and Objective: Finding an effective way to improve body composition and muscular strength with resistance training, has engaged researchers. Previous studies have shown that proper nutrition is one of these ways. The purpose of this study is to review the effect of resistance training accompanied by nutritional education on the body composition and muscular strength in non-athl...

Journal: :Clinical and experimental pharmacology & physiology 2010
Robyn M Murphy

1. Skeletal muscle fibres contain ubiquitous (mu-calpain and m-calpain) and muscle-specific (calpain-3) Ca(2+)-dependent proteases. The physiological roles of the calpains are not well understood, although ubiquitous calpains have been associated with apoptosis and myogenesis and calpain-3 is likely involved in sarcomeric remodelling. A defect in the expression of calpain-3 results in limb-gird...

Journal: :Current Biology 2001
Marie-Christine Mariol Laurent Ségalat

Duchenne muscular dystrophy (DMD) is a progressive degenerative muscular disease that is due to mutations in the dystrophin gene. Neither the function of dystrophin nor the physiopathology of the disease have been clearly established yet. Several groups have reported elevated calcium concentrations in the mdx mouse model of DMD, but the effect of calcium levels on the progression of the disease...

Journal: :archives of anesthesiology and critical care 0
ebrahim espahbodi department of anesthesiology and critical care medicine, farabi hospital, tehran university of medical sciences, tehran, iran. amir abbas yaghooti department of anesthesiology and critical care medicine, farabi hospital, tehran university of medical sciences, tehran, iran. hossein sadrossadat department of anesthesiology and critical care medicine, farabi hospital, tehran university of medical sciences, tehran, iran. mehrdad shoroughi department of anesthesiology and critical care medicine, farabi hospital, tehran university of medical sciences, tehran, iran. alireza ebrahim soltani department of anesthesiology and critical care medicine, farabi hospital, tehran university of medical sciences, tehran, iran. mehrdad goudarzi department of anesthesiology and critical care medicine, farabi hospital, tehran university of medical sciences, tehran, iran.

spinal muscular atrophies (smas) represent a rare group of inherited disorders that cause progressive degeneration of the anterior horn cells of the spinal cord. the exact cause of the degeneration is unknown. loss of these cells results in a progressive lower motor neuron disease that has no sensory involvement and that is manifested as hypotonia, weakness, and progressive paralysis. kugelberg...

Journal: :Neuromuscular disorders : NMD 2011
Gunnar M Buyse Nathalie Goemans Marleen van den Hauwe Daisy Thijs Imelda J M de Groot Ulrike Schara Berten Ceulemans Thomas Meier Luc Mertens

Early mortality in Duchenne muscular dystrophy (DMD) is related to cardiac and respiratory complications. A phase IIa double-blind randomized placebo-controlled clinical trial was conducted to investigate the tolerability and efficacy of idebenone therapy in children with DMD. Twenty-one DMD patients (aged 8-16 years) were randomly assigned to daily treatment with 450 mg idebenone (Catena®) (n=...

A Arzi M Rezaei

L-tyrosine, B6 and folic acid are involved in biosynthesis of DOPA and consequently dopamine. The aim of this study was to investigate the antiparkinsonian effect of these agents in perphenazine-induced catatonia in rats. Murprogo method or scored muscular rigidity, which is induced by a phenothiazine, was used to evaluate the antiparkinsonian effect of these agents. A significant decrease in m...

2005
Seong Woong Kang Yeoun Seung Kang Jae Ho Moon Tae Won Yoo

The aim of this study was to investigate the factors affecting cough ability, and to compare the assisted cough methods in patients with Duchenne muscular dystrophy (DMD). A total seventy-one male patients with DMD were included in the study. The vital capacity (VC) and maximum insufflation capacity (MIC) were measured. The unassisted peak cough flow (UPCF) and three different techniques of ass...

Journal: :Molecular biology of the cell 2007
Nicola Haines Sara Seabrooke Bryan A Stewart

In vertebrates, mutations in Protein O-mannosyltransferase1 (POMT1) or POMT2 are associated with muscular dystrophy due to a requirement for O-linked mannose glycans on the Dystroglycan (Dg) protein. In this study we examine larval body wall muscles of Drosophila mutant for Dg, or RNA interference knockdown for Dg and find defects in muscle attachment, altered muscle contraction, and a change i...

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