BACKGROUND Glycerol monolaurate (GML) is an antimicrobial agent that has potent activity against gram-positive bacteria. This study examines GML antibacterial activity in comparison to lauric acid, in broth cultures compared to biofilm cultures, and against a wide range of gram-positive, gram-negative, and non-gram staining bacteria. METHODOLOGY/PRINCIPAL FINDINGS GML is ≥ 200 times more effe...

Antimicrobial resistance within a wide range of pathogenic bacteria is an increasingly serious threat to global public health. Among these pathogenic bacteria are the highly resistant, versatile and possibly aggressive bacteria, Staphylococcus aureus. Lincosamide antibiotics were proved to be effective against this pathogen. This small, albeit important group of antibiotics is mostly active aga...

Cow urine has been used as medicine since ancient times andthe scriptures of Ayurveda consider cow to be the elixir life. The present study analyzes inhibitory effects fresh at different pH (8.2,4.4,3.8) intervals 5,10, 20,30 days and antibacterial activity was analyzed against Escherichia coli , Staphylococcus aureus Klebsiella sp. It found that no bacterial growth in 3.8 after 30 days. Shelf ...

Bacterial Pathogens Bacteria are the predominant organisms. In the late 1950’s/early 1960’s Gram+ve organisms were the commonest, particularly Staphylococcus aureus. The late 1960’s/early 1970’s were typified by Gram-ve of gastrointestinal tract origin, particularly Escherischia coli, Klebsiella spp and Pseudomonas spp. By the 1990’s Staphylococcus spp including coagulase negative organisms, St...

Polypyrrole/silver (PPy/Ag)nanocomposite was synthesized by a chemical oxidative method. SEM and TEM analyses were performed for studying the morphology of the nanocomposite. It was shown that the obtained nanocomposite particles have a spherical structure with the high surface area to volume ratio that is the important factor in the biological application. The particle sizes of the P...

ISSN: 2319-7706 Volume 4 Number 5 (2015) pp. 172-190 http://www.ijcmas.com Neonatal sepsis is a leading cause of neonatal mortality in developing countries. Identification of the etiological agents of neonatal sepsis is essential for effective treatment. Out of 106 microbial isolates recovered from blood cultures of late onset neonatal sepsis (LONS) patients, only 70 (66 %) isolates were Gram-p...

The authors studied the in vitro antibacterial activity of the photo-activated porphyrin meso-tri(N-methyl-pyridyl), mono(N-tetradecyl-pyridyl)porphine (C14) against four multidrug-resistant bacteria: Staphylococcus aureus, Enterococcus faecalis (Gram-positive), Escherichia coli, Pseudomonas aeruginosa (Gram-negative). Using 10 μg/ml of porphyrin and 60 sec irradiation we observed the remarkabl...

objective(s):isoprenoid biosynthesis is a key metabolic pathway to produce a wide variety of biomolecules such as cholesterol and carotenoids, which target cell membranes. on the other hand, it has been reported that statins known as inhibitors of isoprenoid biosynthesis and cholesterol lowering agents, may have a direct antimicrobial effect on the some bacteria. the exact action of statins in ...

The invasive red palm weevil, Rhynchophorus ferrugineus Olivier (Coleoptera: Curculionidae), is considered one of the world's most devastating insect pests to palm trees. It was observed that larvae of this pest are able to inhibit microbial growth on the rearing media when they start feeding and this observation has led us to study the effect of red palm weevils on various microbial species. T...