نتایج جستجو برای: nos2a gene polymorphism
تعداد نتایج: 1189755 فیلتر نتایج به سال:
there are much heterogeneity in the genetic variation of type 2 diabetes (t2d). the purpose of this study was to investigate the association of seven novel genetic loci identified in a recent genome-wide association studies (gwas) with t2d in chinese dong populations.a case-controlled study was performed in individuals of chinese dong nationality. the genotypes of pard3b (rs849230), loc729993 (...
some of the genotypes of cytokines are associated with acute graft versus host disease after bone marrow transplantation. the purpose of the present investigation was to find out the possible association between transforming growth factor beta-1 (tgf-β1) codon 25 polymorphism (rs:1800471) and acute graft versus host disease (agvhd) after bone marrow transplantation from the sibling with the sim...
background: genetic factors associated with cancer have been widely investigated and several polymorphisms have been connected with breast cancer. breast cancer (bc) can be considered one of the most popular reasons of death among women. bc, likewise, is the second cause of death in iran. the present research aims at determining the frequency of the fibroblast growth factor receptor (fgfr) gene ...
this study has examined the relationship between the xpd lys 751 gln polymorphism and colorectal cancer in 88 patients and their 88 age and sex-matched controls. genomic dna from peripheral whole blood was extracted using standard method to determine the genotype of subjects with rflp-pcr analysis. although this study shows cancer patients harbor more heterozygous genotype (xpd lys 751 gln) (or...
Introduction: The CGA gene encodes alpha subunit of glycoprotein hormones that are involved in the fertility process. The aim of this study was to evaluate the relationship between glycoprotein hormones, alpha polypeptide (CGA) rs6631A> T gene polymorphism with the risk of men with azoospermia or severe oligozoospermia. Methods: This study was conducted in a case-control study on 200 bloo...
Background and purpose: Breast cancer is the most common cancer in women. Most recently C3435T polymorphism of MDR1 gene is considered as one of the major causes of drug resistance in treatment of this disease. This study was conducted to investigate the relationship between C3435T MDR1 gene polymorphism and treatment response in breast cancer patients. Materials and methods: In this longitudi...
Background and Aim: Gestational trophoblastic disease (GTD) is one of complications of pregnancy and has different subtypes (complete mole, partial mole and choriocarcinoma). Macrophage derived factor or CCL22 is a member of chemokines that produced by macrophages, dendritic cells and tumors cells. It has an important role in the recruitment of T regulatory cells and T helper2 lymphocytes to ...
Abstract Background: Schizophrenia is a severe mental disorder and numerous genes and loci are beleived to be involved in this disease. Recent studies have reported a strong genetic association between DTNBP1 (dystrobrevin-binding protein 1) gene variants and schizophrenia. Methods: In this research, we used a case-control study to establish the possible association between the P1635 ...
Background & aims: Metabolic Syndrome (MetS) is a potential threatening factor for cardiovascular disorders and atherosclerosis which is accompanied by increase in plasma triglyceride, cholesterol, low density lipoproteins (LDL-c), fasting blood sugar (FBS) and low high density lipoproteins (HDL-c). Cholesteryl ester transfer protein (CETP) catalysis transfer of lipids and phospholipids betw...
background : a single nucleotide variation within atechol-o-methyl transferase (comt) gene may alter the comt enzyme activity level. polymorphism of val158met in the comt gene has been related to malignancy. in this regard, a study was carried out to find a possible association between the comt gene polymorphism in patients with sporadic prostate cancer (pca) and benign prostatic hyperplasia (...
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