Previous EEG source localization studies in obsessive-compulsive disorder (OCD) reported ambiguous results. The reason probably lies in different OCD samples included in the studies - obsessive-compulsive subjects selected based on a psychopathology questionnaire (the Symptom Checklist - Revised), drug-naïve OCD cases or patients with a long-term disorder. This study was conceived as a replicat...

Obsessive compulsive disorder (OCD) is a type of anxiety disorder characterized by recurrent, intrusive, unwanted thoughts. Research indicates a genetic predisposition for OCD. Many people with OCD have one or more family members who also have it or who may have other anxiety disorders influenced by the brain's serotonin levels, such as panic disorder. Although OCD is a chronic and oftentimes d...

BACKGROUND A high prevalence rate of obsessive-compulsive disorder (OCD) among Hawaiian adolescents, particularly Native Hawaiians, has been reported. Because Native Hawaiian and other Polynesian youth are at an increased risk for rheumatic fever, caused by an autoimmune response to group A beta-hemolytic streptococci, we hypothesized that the genetic and environmental risk factors for streptoc...

The current study evaluated a bifactor model for the Obsessive-Compulsive Inventory Revised (OCI-R) in two samples, with (n=188) and without (n=408) obsessive-compulsive disorder(OCD). Since OCI-R has been traditionally conceptualized as correlated six-factor instrument, our goal was to evaluate fit of against three competing models (one general factor,six factors hierarchical model). Results r...

background and purpose: humans have a capacity to become aware of thoughts and behaviors known as metacognition. the metacognitive model of anxiety disorders emphasizes that metacognitive beliefs are key factors in obsessive-compulsive disorder and depression pathology. the purpose of this research was to compare metacognitive beliefs in patients with obsessive compulsive disorder (ocd) and dep...

Chronic tic disorders (TD), attention-deficit/hyperactivity-disorder (ADHD), and obsessive-compulsive disorder (OCD) frequently co-occur in clinical and epidemiological samples. Family studies have found evidence of shared familial transmission between TD and OCD, whereas the familial association between these disorders and ADHD is less clear. This study aimed to investigate to what extent liab...

Latent inhibition (LI) is a phenomenon that reflects the ability to ignore irrelevant stimuli. LI is attenuated in some schizophrenic patient groups and in high schizotypal normal participants. One study has found enhanced LI in patients with obsessive-compulsive disorder (OCD [Swerdlow, N. R., Hartston, H. J., & Hartman, P. L., 1999. Enhanced visual latent inhibition in obsessive-compulsive di...