نتایج جستجو برای: orphan male adolescent
تعداد نتایج: 384794 فیلتر نتایج به سال:
F atherhood is an important issue to young men surviving cancer as fertility may be impaired by treatment. A number of strategies to preserve fertility are available to adolescent males. Wide variation in practice for adolescent male fertility preservation has previously been shown in North America. No defining data for the UK are available. In the UK, these activities are regulated by the Huma...
Childhood bullying or social stress in adolescent humans is generally considered to increase the risk of developing behavioral disorders like depression in adulthood. Juveniles are hypothesized to be particularly sensitive to stressors in their environment due to the relatively late maturation of brain areas that are targeted by stress such as the prefrontal cortex and hippocampus. In our study...
This paper utilizes existing statistics on adolescent suicide to examine adolescent suicide trends and patterns in Hong Kong for the period 1980 to 2003. Several trends and patterns could be revealed from the analyses. First, there was a gradual rising trend where adolescent suicide rates in the 1990s and the early 2000s were higher than those in the 1980s. Second, suicide rates for adolescents...
BACKGROUND Epilepsy is a serious chronic health condition with a high morbidity impairing the life of patients and afflicted families. Many epileptic conditions, especially those affecting children, are rare disorders generating an urgent medical need for more efficacious therapy options. Therefore, we assessed the output of the US and European orphan drug legislations. METHODS Quantitative a...
Results More orphan drugs were developed in the US during the first ten years of the US Orphan Drug Act (1983-1992, N=73) and during the first ten years of the EU Regulation on Orphan Medicinal products (2000-2009, N=112) than in the EU (2000-2009, N=59). Orphan drug approval was strongly associated with previous experiences of the sponsor in obtaining approval for another orphan drug (OR=17.3,...
The aim of this study was to investigate the relationship between parenting styles and attachment styles with adolescent sleep disorders: the mediating role of Internet addiction. The research method was fundamental in terms of purpose and descriptive-correlational in terms of method. The statistical population of the study included all male and female high school students in Kashan in the acad...
Solid pseudo-papillary tumour of pancreas is a rare neoplasm having a low malignant potential. It mostly affects young adolescent females. We report an unusual case of an 18 year old male with a mass in the mesocolon which was reported as solid pseudo-papillary tumour of pancreas. This case is unusual by virtue of extra pancreatic location and male gender of the patient.
Policy debate about funding criteria for drugs used to treat rare, orphan diseases is gaining prominence. This study presents evidence from a discrete choice experiment using a convenience sample of university students to investigate individual preferences regarding public funding for drugs used to treat rare diseases and common diseases. This pilot study finds that: other things equal, the res...
conclusions the results showed that the prevalence of cigarette smoking in adolescents was high, and the theory of planned behavior (tpb) components were significant predictors of cigarette smoking. it seems that interventions targeting adolescents’ smoking habits might benefit using the tpb model. patients and methods this was a cross-sectional study involving male adolescent students (high sc...
Luminal fluid reabsorption plays a fundamental role in male fertility. We demonstrated that the ubiquitous GPCR signaling proteins Gq and β-arrestin-1 are essential for fluid reabsorption because they mediate coupling between an orphan receptor ADGRG2 (GPR64) and the ion channel CFTR. A reduction in protein level or deficiency of ADGRG2, Gq or β-arrestin-1 in a mouse model led to an imbalance i...
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