PURPOSE We describe two patients with squamous cell papilloma of the conjunctiva due to human papilloma virus (HPV) and review the literature. PATIENTS AND METHODS Two patients with conjunctival tumors were examined and treated in the University Eye Clinic and diagnosed in the University Pathology Department, University Hospital of Ioannina, Greece. The first patient was a 48-year-old man pre...

Induction of cutaneous squamous cell carcinoma (SCC) in mice, by topical chemical [9,10-dimethylbenzanthracene (DMBA) and phorbol 12-myristate 13-acetate (PMA)] application, is a multistep process involving papilloma formation and progression to carcinoma. We have generated a transgenic (Tg) mouse [keratin-14 (K14)-survivin] with skin expression of survivin, an inhibitor of apoptosis expressed ...

Sinonasal tumors may grow to considerable size before presentation and in view of their relation to the base of skull, orbit, cranial nerves and vital vessels; a precise diagnostic and therapeutic planning is needed to achieve the optimal results. We report a case who presented with unilateral nasal blockage, rhinorrhea and episodes of epistaxis which diagnosed as sinonasal inverted papilloma a...

OBJECTIVES To describe an individual with recurrent respiratory papillomatosis that extended into the lung parenchyma and underwent malignant transformation and to discuss the characteristic imaging findings associated with this condition. METHODS The clinical presentation of an individual with this unusual malignant transformation was reviewed. A literature search was performed to characteri...

Inverted papilloma (IP) or Shneiderian papilloma is a benign neoplasm of the sinonasal cavity that is hallmarked by its locally invasiveness, tendency for recurrence and malignant transformation. They arise from the ectodermally derived Scheiderian mucosa that lines the nasal cavity and paranasal sinuses. Predominantly observed in males in their fifth and sixth decade of life, it has an annual ...

BACKGROUND The purpose of this study was to define the optimal surgical strategy for sinonasal inverted papilloma in relation to the site of origin and tumor extent. METHODS Retrospective analysis of patients affected by inverted papilloma treated by purely endoscopic or combined approaches at the Department of Otorhinolaryngology of the University of Brescia and Pavia-Varese from November 19...

The term Schneiderian mucosa refers to the ectodermally derived lining of the nasal cavity and paranasal sinuses, composed generally of stratified ciliated columnar cells, loose abundant lamina propria, and minor salivary glands and their ducts. This unique mucosa may give rise to three distinct histomorphologic papillomas collectively called Schneiderian papillomas. Hyams has described these v...

Benign oropharyngeal tumors are far less common compared to malignant tumors. Oropharyngeal papilloma is present in adults. Squamous papillomas are exophytic masses of oral cavity. When they occur on the palate they are most often asymptomatic and benign. Pedunculated squamous papillomas usually arise from the soft palate, tonsil, or the epiglottis. These lesions can sometimes prove to be fatal...