Vietnam is a fast growing economy in the Asian region with a significantly high population (over 92 million in 2015). Although still expanding (about 1.1% on average during 2000-2015), the Vietnamese population is considered to be entering the ageing stage at a very high rate. The rapid expansion of the middle-income urban class and the ageing people ratio have dramatically pushed up the demand...

BACKGROUND In recent years, China has experienced tremendous growth in its pharmaceutical industry. Both the Chinese government and private investors are motivated to invest into pharmaceutical research and development (R&D). However, studies regarding the different behaviors of public and private investment in pharmaceutical R&D are scarce. Therefore, this paper aims to investigate the current...

This paper analyzes the debate about the ethical conflicts of the methods used by the pharmaceutical industry in the research, production and dissemination of medicines. Three aspects are examined: the involvement of medical professionals with representatives of the pharmaceutical industry; the conflicts of interest regarding their role as sponsors of scientific research; and the evaluation of ...

The rise of biotechnology in the 1970s ushered in a change in innovation strategies in the pharmaceutical industry. The vertically-integrated company become more reliant on a distributed innovation structure in which large corporations integrate the knowledge generated by a network of actors, including small biotechnology firms and public research organisations. In this context, it is important...

BACKGROUND Clinical practice guidelines (CPG) are developed, endorsed, and disseminated through professional medical organizations such as the American Psychiatric Association (APA) as the standard of care for health care providers. Because of their influence, it is critical that CPG are based on objective data, unprejudiced by stakeholder groups, and that any financial associations between aut...

Recently, pharmaceutical R&D has been demanded to increase productivity in terms of time efficiency and innovation as well. There have been discontinuous challenges coming up in this industry, such as globalized R&D competition, stricter regulation, lengthy process of clinical trials, and so on. Considering external changes, high competition, and discontinuities in the industry, it is a good ti...

Three recent systematic reviews have shown that pharmaceutical industry funding of clinical trials is strongly associated with pro-industry results. This article builds on those analyses, situating funding's effects in the context of the ghost-management of research and publication by pharmaceutical companies, and the creation of social ties between those companies and researchers. There are mu...

List of abbreviations 4 Introduction 5 The history and development of the new guideline ICH Topic Q8 5 The contents and requirements according to the new guideline 9 Comparison of the current guideline ICH Q8 with the previous guideline 15 Comparison of both guidelines – a summary 28 The term Design Space-Integration into ICH Q8, Q9 and Q10 29 Requirements of the new guideline for the innovatin...

There is a complex relationship between the pharmaceutical industry and society. The industry, patients, physicians, regulators and politicians are all driven by their own agendas and are subject to sometimes very powerful influences [31]. The primary aims of pharmaceutical companies are, through research, development, production and marketing, to provide new medicines to improve the health of ...