Epithelial-mesenchymal transition (EMT) is defined by the loss of epithelial characteristics and the acquisition of a mesenchymal phenotype. In carcinoma cells, EMT can be associated with increased aggressiveness, and invasive and metastatic potential. To assess the occurrence of EMT in human breast tumors, we conducted a tissue microarray-based immunohistochemical study in 479 invasive breast ...

This study investigated the genetic diversity of bread-wheat genotypes using canopy reflectance-based vegetation indices (VIs) and simple sequence repeat (SSR) marker-based genotyping for drought tolerance. A total 56 wheat were assessed phenotypic traits (combination VIs yield traits) 30 SSR markers. The data averaged over two growing seasons under irrigated drought-stressed conditions. hierar...

xsxsGenomic selection (GS) is an emerging technique for predicting unknown phenotypes using genome-wide marker coverage, allowing the use of efficient computational models to select individuals with high phenotypic values as candidate breeding populations. However, GS remains challenging inefficient crop due limited size training populations, nature genotype-environment interactions, and comple...

Licorice (Glycyrrhiza glabra L.) is a medicinal plant species valued in many countries Asia and Europe for its phytochemical characteristics. biodiversity becoming threatened nowadays Iran due to increasing demand drastic decline of natural habitats. Therefore, licorice domestication would be necessary the near future, molecular breeding help introduce genotypes suitable cultivation. The presen...

Exploring elite alleles based on association analysis of economic traits will promote the breeding, development, and utilization Prunus sibirica resources. This study used 113 P. clones with diverse provenances to perform mapping 20 149 pairs highly polymorphic simple sequence repeat (SSR) markers. Population structure split into three subgroups. General linear model (GLM) mixed (MLM) identifie...

Detection of AmpC and ESBL producing P. aeruginosa by phenotypic methods is challenging, especially in low-income countries such as Pakistan. Therefore, a molecular method was developed for rapid detection these resistance markers. A total 303 clinical samples were collected from intensive care units (ICUs) the Jinnah postgraduate medical centre (JPMC) Karachi, The isolates identified tradition...

Spine gourd (Momordica dioica Roxb.) is a highly nutritious vegetable crop with dioecious reproductive nature. Forty-eight spine genotypes including 32 female and 16 male were assessed for molecular divergence to establish phenotypic relationships using ISSR markers. Twenty-two out of total 25 primers studied yielded 88 bands which 80 polymorphic, three them being unique in their profile. Each ...