background: lipophosphoglycan 3 (lpg3) is required for the lpg assembly, a well known virulent molecule. in this study, the lpg3 gene of the lizard and mammalian leishmania species were cloned and sequenced. a three-dimensional structure (3d) for the target sequence was also predicted by comparative (homology) modeling. materials and methods: an optimization pcr amplification was performed on g...

asthma is a disorder of increasing severity and prevalence. recent knowledge about the pathogenesis of asthma emphasizes its inflammatory nature. cpg oligonucleotides are a class of compounds containing motifs based on the cytosine-guanine dinucleotides (cpg-odns). these motifs are suppressed in mammalian dna. they induce inflammation in mammals characterized by the induction of t helper type 1...

Abstract Background Mitochondrial transcription termination factor (mTERF) is a large gene family which plays significant role during plant growth under various environmental stresses. However, knowledge of mTERF genes in grapevine ( Vitis L.) limited. Results In this research, comprehensive analysis grape VvmTERF ) genes, including chromosome locations, phylogeny, protein motifs, structures, d...

Background: Lipophosphoglycan 3 (LPG3) is required for the LPG assembly, a well known virulent molecule. In this study, the LPG3 gene of the lizard and mammalian Leishmania species were cloned and sequenced. A three-dimensional structure (3D) for the target sequence was also predicted by comparative (homology) modeling. Materials and Methods: An optimization PCR amplification was performed o...

We present solution-state NMR structures for two putative venom peptides from Sicarius dolichocephalus. These peptides were identified from cDNA libraries created from venom gland mRNA and then recombinantly expressed. They are the first structures from any species of Sicarius spiders, and the first peptide structures for any haplogyne spiders. These peptides are homologous to one another, and ...

To examine the effect of concurrent verbal encouragement on the performance of the WAnT in female athletes vs. female non-athletes. College-age female subjects were recruited where ten of the subjects were intercollegiate athletes (ATH, n1 =10) and the nine were non-athletes (NON, n2 =9). The WAnT was novel to all subjects and the subjects were blinded to the study's purpose. Prior to the exper...

The tmRNA-SmpB system releases ribosomes stalled on truncated mRNAs and tags the nascent polypeptides to target them for proteolysis. In many species, mutations that disrupt tmRNA activity cause defects in growth or development. In Caulobacter crescentus cells lacking tmRNA activity there is a delay in the initiation of DNA replication, which disrupts the cell cycle. To understand the molecular...