background:the aim of this study is to find out the spatial and temporal expression of tgf-b1 during the tendon healing, after application of platelet rich plasma (prp). methods: a patellar tendon defect model in rabbits was used for this purpose. 48 skeletally mature new zealand white rabbits, weighing 3.5 kg, were used for this study. equal numbers of animals from both groups were sacrificed ...

There are not many articles about the anatomical knowledge of variable conditions sole foot, but normally this area is essential for surgeries such as reconstructive or peripheral nerve compression syndrome. In region, medial plantar (nervus plantaris medialis) innervates abductor and flexor muscles thumb. addition, there a region where receives skin sensation in foot. When it damaged exposed t...

In mildly hyperosmotic medium, activation of the Na+ -K+ -2Cl- cotransporter (NKCC) counteracts skeletal muscle cell water loss, and compounds that stimulate protein kinase A (PKA) activity inhibit the activation of the NKCC. The aim of this study was to determine the mechanism for PKA inhibition of NKCC activity in resting skeletal muscle. Incubation of rat slow-twitch soleus and fast-twitch p...

Groups of young rats (100 g body wt.) were starved from 23:00 to 11:00 h. The animals were then infused intravenously with diluent or insulin at three different doses to achieve plasma insulin concentrations of 20, 50 and 150 microunits/ml. Before the start of the infusion, animals received a single intravenous injection of indomethacin (250 micrograms) or diluent. After 20 min of infusion, the...

BACKGROUND Clinical tendon injuries represent serious and unresolved issues of the case on how the injured tendons could be improved based on natural structure and mechanical strength. The aim of this studies the effect of aquatic activities and alogenic platelet rich plasma (PRP) injection in healing Achilles tendons of rats. METHODS Forty rats were randomly divided into 5 equal groups. Se...

Background: Delayed tendon healing and tendon adhesions are still found to be among the complications that occur most often after tendon repair. Pistacia khinjuk is one of the three species of Pistacia growing in Iran. Objective: In this study, the role of local injection of ethanolic extract of P. khinjuk was evaluated in healing of the experimental Achilles tendon injury in rabbits. Metho...

The distribution of collagen types I and III and elastin in the developing leg muscles were studied by immunohistochemistry in rat. From 0-day to 8-weeks old, the size of the gastrocnemius and plantaris muscles increased. The muscle connective tissue developed in the order of epimysium, perimysium and finally endomysium. The epimysium contained a considerable amount of collagen types I and III ...

BACKGROUND Lesions in peripheral nerves are highly prevalent in the upper extremity. The present study compares different tendon transfer surgeries in patients with radial nerve palsy. METHODS Fifty patients with radial nerve palsy were randomly selected among patients who referred to Tehran 15th Khordad Hospital during 2006-2011. They were divided into two groups of 17 and 33 subjects. Sing...

Background: Tendon grafting is mostly required to repair an injury to flexor tendon and due to the importance of this tendon; it needs methods to speed up the re-vitality of the tendon allograft. OBJECTIVES: The aim was to investigate the efficacy of the mesenchymal cells and platelet rich plasma on the hydroxyproline content of frozen allograft tendons after grafting in lamb. METHODS: In this ...