Selectively delivering anticancer drugs to solid tumors while avoiding their accumulation in healthy tissues is a major goal polymeric micelle research. We have recently discovered that the extravasation and permeation of micelles occur dynamic manner characterized by vascular bursts followed brief vigorous outward flow fluid (called “nano-eruptions”). Nano-eruptions allow delivery micelle-asso...

objective: tissue engineering is an (interdisciplinary field that applies polymeric scaffolds to control tissue formation in three-dinemtion (3d). the scaffold provides the microenvironment (synthetic temporary extracellular matrix) for regenerative cells, supporting cell attachment, proliferation, differentiation, and neo tissue genesis due to their suitable chemical, physical and biological s...

Nowadays, synthesis and application of Metal Nano-Clusters (MNC) attract great attention of scientists and technologists due to their unique electrical, magnetic and optical properties that differ from those of the bulk material. Nevertheless metallic nanoparticles are sometimes unstable and their stabilization is a crucial point to be solved in order to design new sensing devices which contain...

In this work, we report a nano-fluorophore prepared by polymerization-induced self-assembly (PISA) method based on reversible addition-fragmentation chain transfer polymerization. The macromolecular agent was polyethylene glycol-based trithiocarbonate, and the monomer chalcone derivative terminated with ethylene group. reaction/assembly conducted in dioxane, where nanoparticles extremely unifor...

PURPOSE The purpose of this study was to investigate the in vivo effects of a new smart polymer loaded with dexamethasone on inflamed rabbit eye. MATERIALS AND METHODS Polymeric micelles were prepared using N-isopropylacrylamide (NIPAAM), vinyl pyrrolidone (VP), and methacrylate (MAA) as monomers in the presence of N,N-methylene bis-acrylamide (MBA) and triethyleneglycol dimethacrylate (TEGDM...

In order to provide ultraviolet barrier, antifungal and antibacterial properties, nano-zinc oxide (ZnO) was added lamellar zirconium phosphate (ZrP). The synthesized via reaction of oxychloride octahydrate phosphoric acid following its chemical modification with Jeffamine nano-ZnO. Diffractometric, morphological, thermal, structural relaxometric evaluations were conducted. Fourier transform inf...