Growth of Thermus thermophilus HB27 was inhibited by a proline analog, 3,4-dehydroproline (DHP). This result suggested that the gamma-glutamyl kinase (the product of the proB gene) was inhibited by feedback inhibition in T. thermophilus. DHP-resistant mutants were reported previously for Escherichia coli (A. M. Dandekar and S. L. Uratsu, J. Bacteriol. 170:5943-5945, 1988) and Serratia marcescen...

In mammals that use gut-associated lymphoid tissues for expansion and somatic diversification of the B cell repertoire, B lymphopoiesis occurs early in ontogeny and does not appear to continue throughout life. In these species, including sheep, rabbit, and cattle, little is known about the pathway of B cell development and the time at which B lymphopoiesis wanes. We examined rabbit bone marrow ...

On a closed manifold of dimension greater than one, every smooth weak Riemannian metric on the space of smooth positive probability densities, that is invariant under the action of the diffeomorphism group, is a multiple of the Fisher–Rao metric. Introduction. The Fisher–Rao metric on the space Prob(M) of probability densities is of importance in the field of information geometry. Restricted to...

We consider biobjective shortest path problems in networks with fuzzy arc lengths. Considering the available studies for single objective shortest path problems in fuzzy networks, using a distance function for comparison of fuzzy numbers, we propose three approaches for solving the biobjective prob- lems. The rst and second approaches are extensions of the labeling method to solve the sing...

A ma jo r imped iment to the development of h igh-performance knowledge-based systems arises f rom the p roh ib i t i ve ef for t i n volved in equipping these systems w i t h a suff ic ient set of problem-solv ing methods. Thus , one impo r t an t research prob lem in Machine Learn ing has been the study of techniques for inferr ing problem-solv ing methods f r om examples. A l t hough a numbe...

investigating pressure applied in surface vertically that is done by use of mechanical procedures isn’t efficient to measure pressure applied in inner surface of reservoir or pipes having gas due to entering pressure into whole walls and different surfaces. So, in order to measure this kind of pressure, several studies were conducted in past decades and also various procedures were proposed tha...

Abstract Motivated by applications to a wide range of areas, including assemble-to-order systems, operations scheduling, healthcare and the collaborative economy, we study stochastic matching model on hypergraphs, extending Mairesse Moyal ( J. Appl. Prob. 53 , 2016) case hypergraphical (rather than graphical) structures. We address discrete-event system under random input single items, simply u...