Abstract Introduction Peyronie’s Disease (PD) is prevalent in approximately 7.1% of the general population. Current treatment approaches include medical therapy and surgical intervention, intervention only occurs once disease process has entered chronic, stable phase. The FDA-approved involves use intralesional collagenase clostridium histolyticum injection interventions tunica albuginea plicat...

Background/Objective Platelet-rich plasma (PRP) and hyaluronic acid (HA) injection are both therapeutic options for osteoarthritis and chronic tendinopathy. Although several comparative studies on the two have been published, the effects of mixing PRP and HA are not fully understood. The purpose of this study is to investigate the influence of HA on platelets in PRP by measuring releasing growt...

Objectives. Temporomandibular joint (TMJ) disorders are frequently encountered in the population. Pain is the most common complaint. TMJ luxation needs surgical treatment which has many risks. The objective of this study was to treat TMJ disorders with a minimal invasive method, platelet rich plasma (PRP) injection, instead of surgery. Methods. The study included 7 female patients aged 15 to 42...

Background: Ovarian aging may be reversible. Platelet rich plasma (PRP) has growth factors that promote cellular proliferation and folliculogenesis. Recently published studies case reports suggest ovarian rejuvenation can done by PRP treatment. The objective of the study was to evaluate effect platelet on reserve markers such as anti mullerian hormone (AMH) antral follicle count (AFC) in sub fe...

Renal ischemia-reperfusion injury is a major cause of acute renal failure, causing renal cell death, a permanent decrease of renal blood flow, organ dysfunction and chronic kidney disease. Platelet-rich plasma (PRP) is an autologous product rich in growth factors, and therefore able to promote tissue regeneration and angiogenesis. This product has proven its efficacy in multiple studies, but ha...

Platelet-rich plasma (PRP) has been employed to treat sports injuries to possibly accelerate healing and regeneration. This method offers some potential, especially for athletes. Growth factors are generally prohibited by the World Anti Doping Agency with exception to PRP which may induce adverse effects. The aim of this study was to evaluate any systemic increase of growth factors such as Insu...

We designed a randomized clinical trial with control group, to investigate the effects of platelet rich plasma (PRP) on pain, stiffness, function and quality of life in patients with knee osteoarthritis. Patients were randomly divided in two groups. For both groups of participants, therapeutic exercise was prescribed. In the PRP group, two courses of leukocyte rich PRP (5.6 fold higher platelet...