OBJECTIVE To investigate whether hypertrophy in the dog with chronic atrioventricular block (CAVB) alters [Na+]i and Na/K-pump function of ventricular myocytes. METHODS We measured the [Na+]i dependence of the Na/K pump current, I(p). This relation was used as a calibration curve for [Na+]i based on I(p). We measured I(p) at the time of access and extrapolated [Na+] at the pump sites, i.e. su...

Bone cells (osteoblasts) produce a collagen-rich matrix called osteoid, which is mineralized extracellularly by nanosized calcium phosphate (CaP). Synthetically produced CaP nanoparticles (NPs) have great potential for clinical application. However few studies have compared the effect of CaP NPs with different properties, such as shape and aspect ratio, on the survival and behaviour of active b...

Ni-Fe/Si3N4 nanocomposite coatings with various ratio of Si3N4 to Na-saccharine were prepared by electrodeposition technique. The effect of Si3N4 nanoparticulates in the Ni-Fe nanocomposite coatings was investigated in relation to the ratio of Si3N4 to Na-saccharine in the plating bath. X-ray diffraction analysis showed that the Ni-Fe nanocomposite coating has face center cubic structure (FCC)....

To assess the daily salt intake of people aged 20-74 years based on the 24-hour urinary sodium excretion in urban population of Yazd, a population-based cross-sectional study was conducted. This is a substudy of Yazd Healthy Heart Project in Iran. From 2004 to 2005, two thousand people of the urban population of Yazd city, aged 20-74 years, were enrolled in the main study. Overall, 219 voluntee...

OBJECTIVE To demonstrate if one or more golden relationships between different measurements of the human face exist. MATERIALS AND METHODS To make our measurements, we used three-dimensional (3D) stereophotogrammetry, which has proved to be the "gold standard" in the field of facial anthropometry. We obtained 3D stereophotogrammetric facial acquisitions of 400 healthy young adult subjects, th...

The relative permeability of sodium channels to eight metal cations is studied in myelinated nerve fibers. Ionic currents under voltage-clamp conditions are measured in Na-free solutions containing the test ion. Measured reversal potentials and the Goldman equation are used to calculate the permeability sequence: Na(+) approximately Li(+) > Tl(+) > K(+). The ratio P(K)/P(Na) is 1/12. The permea...

To determine the effect of D-glucose on the beta-cell Na+/K+ pump, 86Rb+ influx was studied in isolated, -cell-rich islets of Umeå-ob/ob mice in the absence or presence of 1mM ouabain. D-glucose (20mM) stimulated the ouabain-sensitive portion of 86Rb+ influx by 65%, whereas the ouabain-resistant portion was inhibited by 48%. The Na+/K+ ATPase activity in homogenates of islets of Umeå-ob/ob mice...

BACKGROUND Bone mineral density (BMD)-based guidelines for bone-directed therapy in women with early breast cancer (EBC) appear inadequate for averting fractures, particularly during aromatase inhibitor (AI) therapy. Therefore, an algorithm was developed to better assess risk and direct treatment (Hadji P, Body JJ, Aapro MS et al. Practical guidance for the management of aromatase inhibitor-ass...

The influence of exogenous application of glycine betaine (GlyBet) was examined on photosynthetic pigments and ions concentration of safflower under salinity stress conditions. The experiment was performed in a randomized complete block design arranged as a factorial with three replications. Salinity treatments (0, 50, 100, and 150 mM) were applied using sodium chloride (NaCl). GlyBet (0, 10, 3...