نتایج جستجو برای: recombinant protein

تعداد نتایج: 1297257  

Background: Lipase enzymes are of great importance in various industries. Currently, extensive efforts have been focused on exploring new lipase producer microorganism as well as genetic and protein engineering of available lipases to improve their functional features. Methods: For screening lipase-producing lactobacilli, isolated strains were inoculated onto tributyrin agar plates. Molecular ...

Masoome Alerasol, Samane Bagheri, Seyed Latif Mousavi Gargari, Shahram Nazarian,

Background: Enterotoxigenic Escherichia coli (ETEC) strains are the major causes of diarrheal disease in humans and animals. Colonization factors and enterotoxins are the major virulence factors in ETEC pathogenesis. For the broad-spectrum protection against ETEC, one could focus on colonization factors and non-toxic heat labile as a vaccine candidate. Methods: A fusion protein is composed of a...

, , Dabaghian, Mehran, Mansouri, Reza, Moghaddam, Farnaz, Taghizadeh, Morteza,

Introduction: According to marked advances in bioinformatics studies, development of influenza vaccines has been greatly modified in many studies. In this study, we have designed a multi-epitope recombinant protein, consisting of several conserved epitopes from Hemagglutinin protein of the H1N1 and H5N1 strains of Influenza virus by immunoinformatics approaches. Materials and Methods: The regis...

Journal: :iranian journal of microbiology 0
zahra arab-mazar infectious diseases and tropical medicine research center, shahid beheshti unversity of medical sciences, tehran, iran shirzad fallahi department of parasitology and mycology, lorestan university of medical sciences, khorramabad, iran ameneh koochaki department of biotechnology, faculty of medicine, shahid beheshti university of medical sciences, tehran, iran hadi mirahmadi infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, iran seyyed javad seyyed tabaei department of parasitology and mycology, shahid beheshti university of medical sciences,tehran, iran

background and objectives: toxoplasma gondii is an obligatory intracellular parasite which causes severe diseases in the fetus of pregnant women and immunocopmromised patients. serological tests based on recombinant protein are one of the main diagnosis methods for the detection of specific antibodies in serum samples. dense granule antigenic proteins derived from t. gondii (tggras) are potenti...

ژودا, پیوتر, حاجی احمدی, فهیمه , سلیمانی اصل, سارا, عربستانی, محمدرضا , مردادی, علیرضا,

Background and purpose: Staphylococcus aureus is an important nosocomial pathogen which causes some diseases such as endocarditis, osteomyelitis, pneumonia, toxic shock syndrome, and food poisoning. The excessive and inappropriate use of antibiotics in the treatment of these diseases causes resistance to many antibiotics. Lysostaphin is an effective agent in the treatment of staphylococcal infe...

Background: Pilot and large-scale production of recombinant proteins requires the presence of stable clones capable of producing large quantities of recombinant proteins. Not only the process of selecting stable clones is time consuming, but also the continuous culturing of clones in large-scale production may cause loss of incoming plasmid and recombinant genes. Thus, considering the advanceme...

Journal: :Antibody reports 2021

The recombinant antibodies AQ806, AS739, AT693, AU197 and AU734 detect by flow cytometry the spike S protein from SARS-CoV-2.

Journal: :Antibody reports 2022


 The recombinant antibodies RB690, RB691, RB692 and RB693 detect by ELISA a synthetic peptide from the Drosophila melanogaster Nop56 protein.

Journal: :vaccine research 0
sm mirnurollahi department of biology, science and research branch, islamic azad university, tehran, iran. sh irani department of biology, science and research branch, islamic azad university, tehran, iran. n davoudi department of biotechnology, pasteur institute of iran, tehran, iran. a bolhassani department of hepatitis and aids, pasteur institute of iran, tehran, iran

introduction: hepatitis c virus (hcv) infection is a major public health problem which influences about 170 million people worldwide. different types of vaccines have been designed using hcv structural proteins to control the viral infection. the core nucleocapsid protein is one of the most conserved proteins and a desirable target for hcv vaccines, especially the protein-based vaccines. in cur...

Background & Aim: Bacterial superantigens, stimulate polyclonal T cells irrespective of their antigen specificity, resulting in a massive release of cytokines from T cells and monocytes, and suggest that that they could be candidates of new antitumor agents. Recent attempts have been done to specifically target superantigens towards tumors. Here, we evaluate TGFαL3-SEB fusion protein as a new a...

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