AIM The aim of this study was to determine plasma Growth Arrest Specific Protein 6 (GAS6) protein levels in patients with unexplained recurrent pregnancy loss (RPL) and compare them to those of pregnant and to healthy non-pregnant women with a history of at least one live delivery. PATIENTS AND METHODS A total of 205 women were included in the study. Of these, 68 were diagnosed with unexplain...

Background Effects of GCSF (Granulocyte Colony-stimulating Factor) injection in patients suffering from recurrent pregnancy loss has been studied in some studies and we now know that transvaginal perfusion of G-CSF might be helpful for improvement of implantation rate among patients with thin endometrium and patients under in vitro fertilization /embryo transfer (IVF/ET) or intracytoplasmic spe...

spontaneous abortion is the most common complication of pregnancy. several lines of evidence indicate that immunologic effector cells may play a role in the pathogenesis of idiopathic repetitive abortions. leukocytes form a substantial proportion of stromal cells in decidua and the endometrial granulated lymphocytes (egl) is the predominant decidual leukocyte population in the first trimester o...

BACKGROUND Recurrent pregnancy loss (RPL) is defined as two or more consecutive pregnancy losses before twenty weeks of gestation. It is caused by a variety of genetics and non-genetics factors. Thyroid autoimmunity could associate with pregnancy loss. OBJECTIVE To investigate the effectiveness of Levothyroxine in treatment of RPL in women with high auto-thyroid antibodies. MATERIALS AND ME...